Sigurthardóttir V, Einarsson B, Sigfússon N, Hartharson T
Islands Universitet, Reykjavík.
Nord Med. 1995;110(4):119-22.
Until recently neither the extent of antihypertensive drug usage in Iceland nor its distribution among drug classes was known. Of the 1,145 men aged 70-84 years alive in 1991, 834 participated in a study carried out by Hjartnavernd, the Heart Association. A history of hypertension or the presence of high blood pressure when measured at the Associations institute were found in 429 men, of whom 157 were on medication for hypertension alone: 95 on single drug treatment, 49 on two drugs, and five on three drugs, no information being available for the remaining eight. The most widely used drugs were diuretics or beta-blockers, of which diuretics apparently yielded better results. Of combined regiments, that of beta-blockers and diuretics was by far the most common, followed by ACE- (angiotensin converting enzyme) inhibitors and diuretics, and beta-blockers and calcium channel blockers. Thus, both medical and economic factors suggest that diuretics should be used in this age group.
直到最近，冰岛抗高血压药物的使用范围及其在各类药物中的分布情况仍不为人所知。1991年在世的1145名70至84岁男性中，有834人参与了由心脏协会Hjartnavernd开展的一项研究。在429名男性中发现有高血压病史或在协会机构测量时存在高血压，其中157人仅接受高血压药物治疗：95人接受单一药物治疗，49人接受两种药物治疗，5人接受三种药物治疗，其余8人没有相关信息。使用最广泛的药物是利尿剂或β受体阻滞剂，其中利尿剂显然效果更好。在联合用药方案中，β受体阻滞剂和利尿剂的组合最为常见，其次是ACE（血管紧张素转换酶）抑制剂和利尿剂，以及β受体阻滞剂和钙通道阻滞剂。因此，医学和经济因素都表明该年龄组应使用利尿剂。
