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对于右心室除颤,一根长而细的电极相当于一根短而粗的电极。

A long thin electrode is equivalent to a short thick electrode for defibrillation in the right ventricle.

作者信息

Leonelli F M, Wright H, Latterell S T, Nelson R S, Adams T P, Kroll M W

机构信息

University of Kentucky, Lexington.

出版信息

Pacing Clin Electrophysiol. 1995 Jan;18(1 Pt 2):221-4. doi: 10.1111/j.1540-8159.1995.tb02508.x.

Abstract

We hypothesized that a long thin right ventricular (RV) electrode would have equivalent defibrillation threshold (DFT) performance to a short thick electrode with approximately the same surface area. This could lead to thinner transvenous lead systems, which would be easier to implant. A thin (5.1 French) lead was compared to a standard control (10.7 French). The thin lead had an 8-cm RV electrode length with a surface area of 4.26 cm2. The standard lead had a RV electrode length of 3.7 cm and a surface area of 4.12 cm2. A 140-mu French capacitor 65%/65% tilt biphasic defibrillation shock was delivered between the RV electrode and a 14-cm2 subcutaneous patch. DFTs were determined following 10 seconds of fibrillation in 11 dogs by a triple determination averaging technique. The thin lead had a lower resistance (77.1 +/- 27.4 omega vs 88.9 +/- 30.3 omega, P < 0.001) than did the thick lead. There was no significant difference in stored energy DFTs (9.9 +/- 2.5 vs 10.3 +/- 2.7, P = 0.098 2-sided, P = 0.049 1- sided). This was in spite of the fact that the long thin lead had a portion of its RV coil extending above the tricuspid valve and, thus, not contributing efficiently to the ventricular gradients in the small dog heart. We conclude that a long thin right ventricular electrode and a standard short thick electrode had equivalent defibrillation performance. This preliminary result should be confirmed in clinical studies as it could lead to significantly thinner transvenous lead systems.

摘要

我们假设,一根细长的右心室(RV)电极与一根表面积大致相同的短粗电极具有相同的除颤阈值(DFT)性能。这可能会产生更细的经静脉导联系统,从而更易于植入。将一根细(5.1法国规格)导联与一个标准对照(10.7法国规格)进行比较。细导联的右心室电极长度为8厘米,表面积为4.26平方厘米。标准导联的右心室电极长度为3.7厘米,表面积为4.12平方厘米。在右心室电极与一个14平方厘米的皮下贴片之间施加140微法国规格电容的65%/65%倾斜双相除颤电击。通过三重测定平均技术,在11只犬发生10秒颤动后测定DFT。细导联的电阻(77.1±27.4欧姆,而粗导联为88.9±30.3欧姆,P<0.001)低于粗导联。储存能量DFT方面无显著差异(9.9±2.5与10.3±2.7,双侧P=0.098,单侧P=0.049)。尽管细长导联的右心室线圈有一部分延伸到三尖瓣上方,因此对小狗心脏的心室梯度贡献不大。我们得出结论,细长的右心室电极和标准的短粗电极具有相同的除颤性能。这一初步结果应在临床研究中得到证实,因为它可能会带来显著更细的经静脉导联系统。

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