Patterson C C, Kernohan W G, Mollan R A, Haugh P E, Trainor B P
Department of Epidemiology and Public Health, Queen's University of Belfast, Northern Ireland.
Paediatr Perinat Epidemiol. 1995 Jan;9(1):90-7. doi: 10.1111/j.1365-3016.1995.tb00121.x.
To determine the incidence of congenital hip dislocation (CDH) a retrospective study was carried out of cases occurring in a defined population using multiple information sources. Of 138,600 children born in the period 1983-1987, a total of 243 were diagnosed with CDH, defined as those requiring splintage or surgery whose treatment extended beyond 6 months of age. Incidence and estimates of relative risks for pre-disposing factors were determined. The rate was 1.75 cases per 1000 livebirths. Major risk factors were female gender and breech presentation. The proportions of cases identified before 1, 3 and 6 months of age were 8, 14 and 35%, respectively. Despite using a restrictive definition, we have obtained an incidence rate among the highest reported in any United Kingdom population. Early detection is widely accepted as desirable, but neonatal screening has proved ineffective.
为确定先天性髋关节脱位(CDH)的发病率,我们利用多种信息来源对特定人群中发生的病例进行了一项回顾性研究。在1983年至1987年期间出生的138,600名儿童中,共有243名被诊断为CDH,定义为那些需要夹板固定或手术治疗且治疗时间超过6个月的儿童。我们确定了发病率以及易患因素的相对风险估计值。发病率为每1000例活产中有1.75例。主要风险因素为女性性别和臀位分娩。在1个月、3个月和6个月龄之前确诊的病例比例分别为8%、14%和35%。尽管采用了严格的定义,但我们得出的发病率在英国所有人群报告的发病率中处于最高之列。早期发现被广泛认为是可取的,但新生儿筛查已被证明无效。