Godward S, Dezateux C
Department of Epidemiology and Public Health, Institute of Child Health, London, UK.
Lancet. 1998 Apr 18;351(9110):1149-52. doi: 10.1016/s0140-6736(97)10466-4.
Universal clinical screening for congenital dislocation of the hip to detect hip instability in neonates was introduced in the UK as a national policy in 1969, but its effectiveness is not known. We aimed to assess the extent to which surgery for congenital dislocation of the hip is the result of a failure of detection through screening or follows non-surgical treatment after detection by screening.
We established a national orthopaedic surveillance scheme and used routine hospital data for inpatients for 20% of births in the UK (Scotland and the Northern and Wessex regions) to ascertain the number of children aged under 5 years per 1000 livebirths who had received at least one operative procedure for congenital dislocation of the hip from April, 1993, to April, 1994. Estimates of the incidence of operative procedures were adjusted for under-ascertainment by capture-recapture techniques.
The ascertainment-adjusted incidence of a first operative procedure for congenital dislocation of the hip in the UK was 0.78 per 1000 livebirths (95% CI 0.72-0-84). Congenital dislocation of the hip had not been detected by routine screening in 222 (70%) of 318 children reported to the national orthopaedic surveillance scheme. In 112 (35%) children the diagnosis was made primarily as a result of parental concern. 67 (21%) children had previously received non-surgical treatment. In Scotland and the Northern and Wessex regions, 81 cases were notified to the national orthopaedic surveillance scheme, 62 cases were identified only through routine hospital data on inpatients, and an estimated 20 cases were not identified by either source, making a total of 163 cases. Thus, 81 (50%) of these 163 cases were identified by surveillance, 125 (77%) by routine data, and 143 (88%) by both sources.
The incidence of a first operative procedure for congenital dislocation of the hip in the UK was similar to that reported before screening was introduced. In most children who received surgery, congenital dislocation of the hip was not detected by screening. Formal evaluation of current and alternative screening policies, including universal primary ultrasound imaging, is needed.
1969年,英国将先天性髋关节脱位的普遍临床筛查作为一项国家政策引入,以检测新生儿的髋关节不稳定情况,但其有效性尚不清楚。我们旨在评估先天性髋关节脱位手术是筛查未发现导致的结果,还是在筛查发现后未进行非手术治疗导致的结果。
我们建立了一个全国性的骨科监测计划,并使用英国20%出生人口(苏格兰以及北部和韦塞克斯地区)住院患者的常规医院数据,以确定1993年4月至1994年4月期间每1000例活产中5岁以下接受过至少一次先天性髋关节脱位手术的儿童数量。通过捕获-再捕获技术对手术发生率的估计进行了未完全确定的调整。
英国先天性髋关节脱位首次手术的确定调整后发生率为每1000例活产0.78例(95%可信区间0.72 - 0.84)。在向全国骨科监测计划报告的318名儿童中,222名(70%)先天性髋关节脱位未通过常规筛查发现。在112名(35%)儿童中,诊断主要是由于家长的担忧。67名(21%)儿童此前接受过非手术治疗。在苏格兰以及北部和韦塞克斯地区,81例病例被报告给全国骨科监测计划,62例仅通过住院患者的常规医院数据确定,估计有20例两种来源均未发现,共计163例。因此,这163例病例中,81例(50%)通过监测发现,125例(77%)通过常规数据发现,143例(88%)通过两种来源均发现。
英国先天性髋关节脱位首次手术的发生率与引入筛查之前报告的发生率相似。在大多数接受手术的儿童中,先天性髋关节脱位未通过筛查发现。需要对当前和替代筛查政策,包括普遍的初级超声成像进行正式评估。