Pardo J, Meruane J, Staeding J, Drago G, Etchart M
Servicio de Cardiología, Reumatología y Anatomía Patológica, Hospital Militar, Santiago de Chile.
Rev Med Chil. 1995 May;122(5):550-5.
A 41 years old woman with polymyositis-dermatomyositis with cardiac involvement is presented. The patient evolved with congestive heart failure, the electrocardiogram showed a left anterior hemiblock, lack of progression of R waves from V1 to V4 and unspecific ST and T alterations. Echocardiogram and cardiac catheterization showed global ventricular disfunction and pulmonary hypertension. An endomyocardial biopsy performed at the apex of the right ventricle showed mononuclear inflammatory infiltration, myocardial fiber degeneration and fibrosis. Initially, the patient responded well to diuretic, vasodilator and steroid therapy. Posteriorly she developed an atrial flutter that required electrical cardioversion and later died suddenly during the course of an acute pneumonia.
本文报告了一名41岁患有多肌炎-皮肌炎并累及心脏的女性患者。该患者出现充血性心力衰竭，心电图显示左前分支阻滞，V1至V4导联R波无进展以及非特异性ST段和T波改变。超声心动图和心导管检查显示全心功能障碍和肺动脉高压。在右心室心尖处进行的心内膜心肌活检显示单核细胞炎性浸润、心肌纤维变性和纤维化。最初，患者对利尿剂、血管扩张剂和类固醇治疗反应良好。后来她出现了心房扑动，需要进行电复律，随后在急性肺炎病程中突然死亡。
