Bar-Dayan Y, Small M
Department of Cell Biology and Histology, Sackler School of Medicine Tel Aviv University, Ramat Aviv, Israel.
Thymus. 1994;23(2):95-101.
Age-related decline of the thymus in mice was reversed by repeated injections of bovine growth hormone. After hormone administration that was begun at 5, 8, or 11.5 months of age, the cortical volume fraction (Vc), cortical/medullary ratio (C/M) and thymocyte numbers found were in the range obtained with younger mice. Growth hormone injection reduced the slope of the curves for Vc and C/M as a function of age, indicating a slowing down of the involution process.
通过反复注射牛生长激素可逆转小鼠胸腺与年龄相关的衰退。在5、8或11.5月龄开始给予激素后，所测得的皮质体积分数（Vc）、皮质/髓质比（C/M）和胸腺细胞数量均处于较年轻小鼠的范围内。生长激素注射降低了Vc和C/M随年龄变化曲线的斜率，表明退化过程减缓。
