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路易斯安那州羔羊体内对伊维菌素耐药的捻转血矛线虫

Ivermectin resistant Haemonchus contortus in Louisiana lambs.

作者信息

Miller J E, Barras S R

机构信息

Department of Animal Science, Louisiana Agricultural Experiment Station, Louisiana State University Agricultural Center, Baton Rouge 70803-4210.

出版信息

Vet Parasitol. 1994 Dec;55(4):343-6. doi: 10.1016/0304-4017(94)90074-4.

Abstract

Fifteen weaned crossbred (Suffolk x Louisiana Native) lambs were treated with albendazole (10 mg kg-1) to remove existing nematode infections. They were inoculated with Haemonchus contortus infective larvae from a residual population surviving treatment with the oral formulation of ivermectin (0.2 mg kg-1). One group of five lambs remained untreated, another group of five was treated with the injectable formulation of ivermectin (0.2 mg kg-1), and a third group of five was treated with the oral formulation of ivermectin (0.2 mg kg-1). Subsequent to the treatments, there was essentially no difference in mean fecal egg count or mean number of H. contortus recovered at necropsy between the three groups.

摘要

15只断奶的杂交(萨福克×路易斯安那本地品种)羔羊用阿苯达唑(10毫克/千克)进行治疗,以清除现有的线虫感染。它们接种了来自用伊维菌素口服制剂(0.2毫克/千克)治疗后存活的残留群体的捻转血矛线虫感染性幼虫。一组5只羔羊不进行治疗,另一组5只用伊维菌素注射制剂(0.2毫克/千克)治疗,第三组5只用伊维菌素口服制剂(0.2毫克/千克)治疗。治疗后,三组之间在平均粪便虫卵计数或尸检时回收的捻转血矛线虫平均数量上基本没有差异。

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