Department of Veterinary Parasitology and Entomology, University of Nigeria, Nsukka, Nigeria.
Parasitol Res. 2012 Oct;111(4):1683-7. doi: 10.1007/s00436-012-3007-6. Epub 2012 Jul 4.
Faecal egg count reduction test was used to evaluate the efficacy of levamisole and ivermectin in the control of bovine parasitic gastroenteritis in a part of Nigeria not previously surveyed. Ninety (90) randomly selected N'dama cattle from two herds in Nsukka, Enugu State of Nigeria, were studied. The animals were divided into two groups, namely, levamisole and ivermectin treatment groups. Faecal samples were collected prior to the administration of the respective anthelmintic and faecal egg count/gram of faeces determined. Post-treatment faecal samples were collected after 10 and 14 days of levamisole and ivermectin administration, respectively, and faecal egg count (FEC) determined. Thereafter, the faecal egg count reduction was calculated based on the formula [Formula: see text]. Pooled faecal samples for the respective treatment groups were cultured for larval identification and count. Pre-treatment FEC showed that the animals were readily infected with gastrointestinal nematodes with mean FEC of 233.0 ± 35.13 and 302.0 ± 19.94, respectively, for the levamisole- and ivermectin-treated groups. Post-treatment FEC of 0 was recorded for both groups, showing a 100% reduction of the pre-treatment faecal egg count. We concluded that the anthelmintics used in this work were very effective in the control of bovine parasitic gastroenteritis in the study areas, and no resistance was detected.
采用粪便卵计数减少试验来评估左旋咪唑和伊维菌素在控制尼日利亚未调查地区的牛寄生性胃肠炎方面的疗效。从尼日利亚埃努古州恩苏卡的两个牛群中随机选择了 90 头 N'dama 牛进行研究。这些动物被分为两组，即左旋咪唑和伊维菌素治疗组。在给予各自的驱虫药之前采集粪便样本，并确定粪便中每克粪便的卵数。在给予左旋咪唑和伊维菌素后 10 天和 14 天分别采集粪便样本并进行粪便卵计数（FEC）。然后，根据公式[公式：见文本]计算粪便卵计数减少率。对各自的治疗组的混合粪便样本进行培养以鉴定和计数幼虫。治疗前 FEC 表明，动物很容易感染胃肠道线虫，左旋咪唑和伊维菌素治疗组的平均 FEC 分别为 233.0 ± 35.13 和 302.0 ± 19.94。两组的治疗后 FEC 均为 0，表明治疗前粪便卵计数减少了 100%。我们得出结论，在研究区域，所用的驱虫药在控制牛寄生性胃肠炎方面非常有效，且未检测到耐药性。
