Ugriné-Hunyadvári E, Kissné Koczka C
Szent-Györgyi Albert Orvostudományi Egyetem Gyógyszertechnológiai Intézet, Szeged.
Acta Pharm Hung. 1995 Jan;65(1):15-21.
Authors studied potentials for isotonizability and isohydria adjustment of viscous eye-drops. Various non-ionic, anionic, linear chain, and/or crosslinked polymers were applied in order to increase viscosity. They have found that rheological features of the solutions do not change either upon the addition of electrolytes or upon change in pH value. Modification in equilibrium viscosity values indicate the onset of dehydration. Such change occurs in concentrated polymer solutions only.