Ugriné Hunyadvári E, Tóthné Kiss G, Kissné Koczka C
Szent-Györgyi Albert Orvostudományi Egyetem Gyógyszertechnológiai Intézet, Szeged.
Acta Pharm Hung. 1995 Mar;65(2):41-4.
Therapeutical effect of ophthalmological solutions is markedly influenced by their surface tension which is also responsible for the irritating effect of the eye drop. Authors studied the effect of different polymers on surface tension. They found that each of the water soluble polymers studied decreased the surface tension of solutions against air. This surface tension decreasing effect is independent from the concentration of the solution. Its value is slightly influenced by the pH of the solution, while it is increased by its electrolyte content.
眼科溶液的治疗效果受到其表面张力的显著影响,而表面张力也是滴眼液产生刺激作用的原因。作者研究了不同聚合物对表面张力的影响。他们发现,所研究的每种水溶性聚合物都会降低溶液与空气接触时的表面张力。这种降低表面张力的效果与溶液浓度无关。其数值受溶液pH值的影响较小,而受电解质含量的影响则会增大。