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一种预防上呼吸道感染的口服抗原试验。1973 - 1974年第二年的结果。

Trial of an oral antigen against upper respiratory-tract infection. Results in the second year (1973-74).

作者信息

Price H C, Henley G

出版信息

Practitioner. 1976 Mar;216(1293):341-6.

PMID:772665
Abstract

A double-blind trial in two randomly structured groups of boarders (44 girls and 66 boys) aged 7 to 13 years was undertaken in two Bristrol schools. Dosage was 1 ml a day of fluid (antigen or placebo) orally for the first four weeks of the autumn term, absenteeism being the main parameter measured, using a structured recording code. There was a highly significant difference in the number of days lost from upper respiratory-tract infection in the treated as opposed to the placebo group (x2 = 40-00 P less than 0-001 (v = 1). The number of colds was also significantly lower in the treated group (x2 = 8-05 P less than 0-005 (V less than i)).

摘要

在布里斯托尔的两所学校,对两组年龄在7至13岁、随机分组的寄宿生(44名女孩和66名男孩)进行了一项双盲试验。在秋季学期的前四周,每天口服1毫升液体(抗原或安慰剂),使用结构化记录代码,将缺勤率作为主要测量参数。与安慰剂组相比,治疗组因上呼吸道感染而缺勤的天数有极显著差异(x2 = 40.00,P小于0.001(v = 1))。治疗组的感冒次数也显著较低(x2 = 8.05,P小于0.005(V小于1))。

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