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伴有骨髓纤维化和白血病的Sweet综合征:对干扰素的部分反应

Sweet's syndrome with myelofibrosis and leukemia: partial response to interferon.

作者信息

Brodkin R H, Schwartz R A

机构信息

Dermatology, New Jersey Medical School, Newark, USA.

出版信息

Dermatology. 1995;190(2):160-3. doi: 10.1159/000246669.

DOI:10.1159/000246669
PMID:7727840
Abstract

Sweet's syndrome with malignancy or acute neutrophilic dermatosis (AND) is an unusual cutaneous disorder seen most commonly in association with acute myelogenous leukemia. A large majority of patients with AND and malignancy have neoplasms of hematopoietic, plasma cell or lymphoid nature. The patient reported here had myelofibrosis, chronic myelogenous leukemia and Sweet's syndrome. The individual lesions responded to intralesional interferon-alpha 2, which has not to our knowledge been reported previously. This result, however, was not as great as the response of AND to intralesional steroid injections.

摘要

伴有恶性肿瘤的Sweet综合征或急性中性粒细胞性皮肤病(AND)是一种不常见的皮肤疾病,最常与急性髓系白血病相关。大多数患有AND和恶性肿瘤的患者患有造血、浆细胞或淋巴性质的肿瘤。本文报道的患者患有骨髓纤维化、慢性髓系白血病和Sweet综合征。单个皮损对皮损内注射α-2干扰素有效,据我们所知,此前尚无相关报道。然而,这一结果不如AND对皮损内注射类固醇的反应显著。

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Sweet's syndrome with myelofibrosis and leukemia: partial response to interferon.伴有骨髓纤维化和白血病的Sweet综合征:对干扰素的部分反应
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引用本文的文献

1
Insights Into the Pathogenesis of Sweet's Syndrome.Sweet 综合征发病机制的研究进展。
Front Immunol. 2019 Mar 12;10:414. doi: 10.3389/fimmu.2019.00414. eCollection 2019.
2
An atypical presentation of Sweet's syndrome in a myelofibrosis patient.一名骨髓纤维化患者出现Sweet综合征的非典型表现。
BMJ Case Rep. 2019 Mar 9;12(3):e228076. doi: 10.1136/bcr-2018-228076.
3
Sweet's syndrome with idiopathic thrombocythemia.伴特发性血小板增多症的Sweet综合征
Postepy Dermatol Alergol. 2014 Feb;31(1):47-52. doi: 10.5114/pdia.2014.40661. Epub 2014 Feb 25.
4
Sweet's syndrome--a comprehensive review of an acute febrile neutrophilic dermatosis.斯威特综合征——急性发热性嗜中性皮病的全面综述
Orphanet J Rare Dis. 2007 Jul 26;2:34. doi: 10.1186/1750-1172-2-34.