Brodkin R H, Schwartz R A
Dermatology, New Jersey Medical School, Newark, USA.
Dermatology. 1995;190(2):160-3. doi: 10.1159/000246669.
Sweet's syndrome with malignancy or acute neutrophilic dermatosis (AND) is an unusual cutaneous disorder seen most commonly in association with acute myelogenous leukemia. A large majority of patients with AND and malignancy have neoplasms of hematopoietic, plasma cell or lymphoid nature. The patient reported here had myelofibrosis, chronic myelogenous leukemia and Sweet's syndrome. The individual lesions responded to intralesional interferon-alpha 2, which has not to our knowledge been reported previously. This result, however, was not as great as the response of AND to intralesional steroid injections.
伴有恶性肿瘤的Sweet综合征或急性中性粒细胞性皮肤病(AND)是一种不常见的皮肤疾病,最常与急性髓系白血病相关。大多数患有AND和恶性肿瘤的患者患有造血、浆细胞或淋巴性质的肿瘤。本文报道的患者患有骨髓纤维化、慢性髓系白血病和Sweet综合征。单个皮损对皮损内注射α-2干扰素有效,据我们所知,此前尚无相关报道。然而,这一结果不如AND对皮损内注射类固醇的反应显著。