Lomnyts'ka V B, Kolotylova L V, Nemchenko O O, Saad A S, Prun'ko T D, Lutsyk T S
Mikrobiol Z. 1995 Jan-Feb;57(1):59-63.
The results of six-year-long investigations of microbiological indices of pneumococcal microflora in healthy carriers and in children with chronic respiratory pathology are presented in the paper. Peculiarities of pneumococcal contamination of nasopharynx mucosa in the both groups were detected. A difference in the intensity of pneumococcus colonization and localization in upper respiratory tract between healthy and sick children was found. Data on adhesive and lysozyme activity of the obtained stocks as factors favourable for microflora contamination and persistence on nasopharynx mucosa are given. An analysis of antibiograms of the obtained pneumococcus cultures was performed. The recent trend of preservation of pneumococcus sensitivity to the main groups of commonly used antibiotic preparations has been affirmed.
本文介绍了对健康携带者和患有慢性呼吸道疾病的儿童肺炎球菌微生物群微生物学指标进行的为期六年的调查结果。检测了两组鼻咽黏膜肺炎球菌污染的特点。发现健康儿童和患病儿童在上呼吸道肺炎球菌定植强度和定位方面存在差异。给出了所获得菌株的黏附活性和溶菌酶活性数据，这些因素有利于微生物群在鼻咽黏膜上的污染和持续存在。对所获得的肺炎球菌培养物的抗菌谱进行了分析。证实了肺炎球菌对常用抗生素制剂主要类别仍保持敏感性的最新趋势。
