Hameed K, Gibson T, Kadir M, Sultana S, Fatima Z, Syed A
Department of Medicine and Community Health Services, Aga Khan University Hospital, Karachi, Pakistan.
Br J Rheumatol. 1995 Mar;34(3):252-6. doi: 10.1093/rheumatology/34.3.252.
Using previously applied methods a survey of joint symptoms was undertaken among 4232 adults, evenly distributed between affluent and poor areas of Karachi, Pakistan. Only six cases of definite rheumatoid arthritis (RA) (1958 ARA criteria) were identified in the 245 persons who complained of joint problems of at least 4 weeks duration. The prevalence was 0.9 [confidence interval (CI) 0.21-3.61] and 1.98 (CI 0.55-5.1) per thousand in the poor and affluent districts, respectively. These were substantially less than prevalence rates reported in the West but were similar to figures derived from other developing countries. There was no obvious impact of current living standards on the findings. The relative paucity of older female subjects in both the affluent and poor communities may account at least in part for the low rates observed. The infrequency of rheumatoid nodules in Southern Asians with RA illustrates the difficulty of applying existing diagnostic criteria to this community.
采用先前应用的方法，对4232名成年人进行了关节症状调查，这些成年人在巴基斯坦卡拉奇的富裕和贫困地区平均分布。在245名主诉关节问题至少持续4周的人中，仅发现6例确诊类风湿性关节炎（RA）（1958年美国风湿病学会标准）。贫困和富裕地区的患病率分别为每千人0.9[置信区间（CI）0.21 - 3.61]和1.98（CI 0.55 - 5.1）。这些患病率大大低于西方报道的患病率，但与其他发展中国家得出的数据相似。当前生活水平对调查结果没有明显影响。富裕和贫困社区中老年女性受试者相对较少，这可能至少部分解释了观察到的低患病率。南亚类风湿性关节炎患者中类风湿结节罕见，这说明了将现有诊断标准应用于该社区的困难。
