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土耳其伊兹密尔城市人口中类风湿关节炎的患病率。

The prevalence of rheumatoid arthritis in an urban population of Izmir-Turkey.

作者信息

Akar S, Birlik M, Gurler O, Sari I, Onen F, Manisali M, Tirpan K, Demir T, Meral M, Akkoc N

机构信息

Dokuz Eylul University School of Medicine, Division of Rheumatology, Dokuz Eylul University, Izmir, Turkey.

出版信息

Clin Exp Rheumatol. 2004 Jul-Aug;22(4):416-20.

Abstract

OBJECTIVE

To estimate the prevalence of rheumatoid arthritis (RA) in an urban area in Izmir, Turkey.

METHODS

The study was conducted in the Balcova and Narlidere districts of Izmir and a total of 2,887 people aged 20 years or older were contacted with a 98.2% acceptance rate. Nine medical doctors administered an RA questionnaire by face-to-face interview. Subjects reporting a history of swelling in at least 2 joints lasting more than 4 continuous weeks or a history of a diagnosis of rheumatoid arthritis, inflammatory joint rheumatism or joint rheumatism were considered as screening positive and they were invited to come in for an examination. RA cases were defined by the 1987 American College of Rheumatology (ACR) criteria modifiedfor use in population studies.

RESULTS

A total of 301 subjects (243 women, 58 men), or 10.6% of those who received the questionnaire were screening positive. 240 (79.7%) of these agreed to undergo a clinical examination either in the clinic or at home. Among these, 14 (12 female, 2 male) patients fulfilled the ACR criteria for RA. The prevalence of RA was 0.49% (95% CI 0.27-0.83) in the total population interviewed, 0.77% (95% CI 0.40-1.35) in women and 0.15% (95%CI 0.02-0.60) in men. The age- and sex-adjusted prevalence for the general population was estimated as 0.36%. Five of the 14 RA (36%) cases had not been diagnosed previously

CONCLUSION

These data are consistent with the results of other Mediterranean countries. A significant proportion of RA cases remain undiagnosed in the community.

摘要

目的

评估土耳其伊兹密尔一个市区类风湿关节炎(RA)的患病率。

方法

研究在伊兹密尔的巴尔乔瓦和纳尔利代雷区开展,共联系了2887名20岁及以上的人群,接受率为98.2%。九名医生通过面对面访谈发放RA问卷。报告至少两个关节肿胀持续超过4周或有类风湿关节炎、炎性关节风湿病或关节风湿病诊断史的受试者被视为筛查阳性,并被邀请前来检查。RA病例根据1987年美国风湿病学会(ACR)标准进行定义,并针对人群研究进行了修改。

结果

总共301名受试者(243名女性,58名男性),即接受问卷者的10.6%为筛查阳性。其中240名(79.7%)同意在诊所或家中接受临床检查。在这些人中,14名(12名女性,2名男性)患者符合RA的ACR标准。在接受访谈的总人口中,RA的患病率为0.49%(95%可信区间0.27 - 0.83),女性为0.77%(95%可信区间0.40 - 1.35),男性为0.15%(95%可信区间0.02 - 0.60)。总体人群经年龄和性别调整后的患病率估计为0.36%。14例RA病例中有5例(36%)此前未被诊断。

结论

这些数据与其他地中海国家的结果一致。社区中相当一部分RA病例仍未被诊断。

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