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The formation of peroxynitrite in vivo from nitric oxide and superoxide.

作者信息

Squadrito G L, Pryor W A

机构信息

Biodynamics Institute, Louisiana State University, Baton Rouge 70803, USA.

出版信息

Chem Biol Interact. 1995 May 19;96(2):203-6. doi: 10.1016/0009-2797(94)03591-u.

Abstract

Peroxynitrite is predicted to be formed in vivo from the reaction of nitric oxide and superoxide. Nitric oxide at concentrations as low as 3 nM is expected to compete efficiently for superoxide near the surface of endothelial cells, based on competition kinetics.

摘要

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