Nanayakkara B
General Hospital, Anuradhapura, Sri Lanka.
Ceylon Med J. 1994 Dec;39(4):160-2.
To determine the variation in arterial oxygen saturation during intravenous ketamine anaesthesia while breathing air.
Prospective study.
General Hospital, Anuradhapura.
65 patients of both sexes between the ages 10 to 60 years scheduled for minor surgery lasting five to 15 minutes were selected. Anaesthesia was induced with intravenous diazepam and ketamine and patients were allowed to breathe air.
Arterial oxygen saturation, respiratory rate, degree of analgesia both during and one hour after surgery, incidence of nausea, vomiting and hallucinations after recovery were recorded.
Five patients (7.6%) showed a fall in oxygen saturation to less than 90%. Three of them had airway obstruction and the other two were obese. Nausea and vomiting occurred in eight patients (12%). Hallucinations were noted in five patients (7%). Postoperative analgesia was present one hour after surgery in 54 patients (83%).
Young and otherwise healthy patients maintained normal oxygen saturation while breathing air provided airway patency is maintained. However, facilities for administration of oxygen, intubation and ventilation should be available during ketamine anaesthesia.
确定静脉注射氯胺酮麻醉期间呼吸空气时动脉血氧饱和度的变化。
前瞻性研究。
阿努拉德普勒综合医院。
选择65例年龄在10至60岁之间计划进行持续5至15分钟小手术的男女患者。静脉注射地西泮和氯胺酮诱导麻醉，患者呼吸空气。
记录手术期间及术后1小时的动脉血氧饱和度、呼吸频率、镇痛程度、恢复后恶心、呕吐和幻觉的发生率。
5例患者（7.6%）血氧饱和度降至90%以下。其中3例有气道阻塞，另外2例为肥胖患者。8例患者（12%）出现恶心和呕吐。5例患者（7%）出现幻觉。54例患者（83%）术后1小时仍有镇痛效果。
年轻且其他方面健康的患者在呼吸空气且气道通畅的情况下可维持正常血氧饱和度。然而，氯胺酮麻醉期间应具备给氧、插管和通气设施。
