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患有卡波西肉瘤的老年男性的流感嗜血杆菌菌血症:两例报告及文献综述

Hemophilus influenzae bacteremia in elderly men with Kaposi's sarcoma: two case reports and a review of the literature.

作者信息

Arbiser J L, Katz J

机构信息

Department of Dermatology, Harvard Medical School, Massachusetts General Hospital, Boston 02114, USA.

出版信息

Cutis. 1995 Feb;55(2):101-3.

PMID:7729153
Abstract

Hemophilus influenzae is a common pathogen responsible for respiratory infections, meningitis, and bacteremia in children, and a rare cause of bacteremia in adults. We report two cases of H. influenzae bacteremia in elderly men with Kaposi's sarcoma. Both of the patients described are elderly men with no other stigmata of the acquired immune deficiency syndrome. Both Kaposi's sarcoma of the elderly and adult H. influenzae bacteremia are relatively uncommon, and the coappearance of these syndromes may suggest a common immune defect predisposing to these syndromes, or Kaposi's sarcoma may provide a portal of entry for this organism. We suggest that patients with Kaposi's sarcoma who may have bacteremia receive appropriate antibiotic treatment for H. influenzae until a causative agent is isolated.

摘要

流感嗜血杆菌是导致儿童呼吸道感染、脑膜炎和菌血症的常见病原体,也是成人菌血症的罕见病因。我们报告了两例患有卡波西肉瘤的老年男性发生流感嗜血杆菌菌血症的病例。所描述的两名患者均为老年男性,无其他获得性免疫缺陷综合征的体征。老年卡波西肉瘤和成人流感嗜血杆菌菌血症都相对不常见,这些综合征的同时出现可能提示存在导致这些综合征的共同免疫缺陷,或者卡波西肉瘤可能为该病原体提供了一个侵入途径。我们建议,可能发生菌血症的卡波西肉瘤患者在分离出病原体之前,接受针对流感嗜血杆菌的适当抗生素治疗。

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