Cantwell A R
Cutis. 1983 Jul;32(1):58-61, 63-4, 68.
Current epidemiologic data suggest that a possible infectious and contagious microbial agent is responsible for the recent outbreak of Kaposi's sarcoma and the acquired immunodeficiency syndrome affecting young homosexual men. In this histopathologic study, rare foci of acid-fast, and Giemsa-stained coccoid forms, and more rare foci of Gram-variable coccoid forms, were observed within the microscopic skin biopsy specimens from two young homosexual men with Kaposi's sarcoma. These findings, in addition to other previously reported histopathologic findings of similar bacteria in vivo in "typical" cases of Kaposi's sarcoma occurring in elderly Jewish men, suggest that bacteria may be implicated in the pathogenesis of Kaposi's sarcoma.
目前的流行病学数据表明，一种可能具有传染性的微生物病原体是近期卡波西肉瘤爆发以及影响年轻同性恋男性的获得性免疫缺陷综合征的病因。在这项组织病理学研究中，在两名患有卡波西肉瘤的年轻同性恋男性的皮肤活检标本显微镜检查中，观察到了罕见的抗酸和吉姆萨染色的球状形态病灶，以及更罕见的革兰氏可变球状形态病灶。这些发现，连同之前在老年犹太男性“典型”卡波西肉瘤病例体内类似细菌的其他组织病理学发现，表明细菌可能与卡波西肉瘤的发病机制有关。
