Krakau C E
Department of Ophthalmology, University Eye Clinic, Malmö, Sweden.
Graefes Arch Clin Exp Ophthalmol. 1995 Feb;233(2):112-8. doi: 10.1007/BF00241481.
The aim was to elucidate two controversial questions. (1) is the pulsatile inflow dominant or is there a sizeable steady inflow component? (2) Is the outflow of blood steady or pulsatile in induced and in glaucomatous hypertension?
The OBF system (Langham) was used for pulse recording. A simple electric flow model was conceived and analysed in terms of Fourier series, using linear circuit theory.
Possible explanations of the seemingly inconsistent observations are indicated by the model. (1) A steady inflow of similar magnitude to the pulsatile one is predicted. The total flow can be determined at present theoretically from recordings of the pulsatile inflow and of the systolic and diastolic intraocular blood pressure. Some methodological improvements are desirable in order to obtain reliable estimates in practice. (2) The outflow is normally steady, probably even in ocular hypertension and glaucoma. In hypertension induced with the suction cup this may be doubted. The eye has similarities with the device called the Starling resistor which describes the behaviour of collapsible vessels. Acute pressure increase (plus the pulsations of the IOP) may put the collapsible vessels into a state which disturbs the steady outflow. The effects of changes in IOP and in other components on the size and shape of the flow curve are demonstrated.
目的是阐明两个有争议的问题。（1）搏动性流入占主导还是存在相当大的稳定流入成分？（2）在诱导性高血压和青光眼性高血压中，血液流出是稳定的还是搏动性的？
使用OBF系统（兰厄姆）记录脉搏。构建了一个简单的电流模型，并根据线性电路理论用傅里叶级数进行分析。
该模型指出了对看似不一致的观察结果的可能解释。（1）预测存在与搏动性流入量相似的稳定流入。目前理论上可根据搏动性流入以及收缩期和舒张期眼内血压的记录来确定总流量。为了在实践中获得可靠的估计，需要一些方法上的改进。（2）流出通常是稳定的，甚至在高眼压症和青光眼患者中可能也是如此。对于用吸盘诱导的高血压，这一点可能存疑。眼睛与称为斯塔林电阻器的装置有相似之处，该装置描述了可塌陷血管的行为。眼压急性升高（加上眼压的搏动）可能使可塌陷血管进入一种扰乱稳定流出的状态。展示了眼压和其他成分变化对流量曲线大小和形状的影响。
