Gelinov Kh, Belovezhdov N
Vutr Boles. 1976;15(1):59-65.
The results from the comparative clinical studies on the effectiveness of tetraolean and tetracycline are summed up about 1672 patients with acute and exacerbated infections of the respiratory organs (1036 patient, treated by ten teams, working on the theme given in advance "Comparative clinical studies between tetraolean and tetracyclin in acute pneumonia", 164 patients with postgrippe viral-bacterial pneumonia, treated during the grippe epidemy 1972/1973 and 445 patient treated at the Therapeutic Clinic, Sofia during 1967-1972). The total results reveal that, according to the adopted objective indices, the therapeutic effect of tetraolean is with a statistically significant superiority over tetracyclin. The beneficial results obtained in the treatment of 14 patients with endocarditis lenta are also reported. The mechanisms of that superior effect, defined as "clinical synergism" are discussed.
对1672例呼吸器官急性和加重感染患者进行了关于四萜醇和四环素疗效的比较临床研究（1036例患者由十个团队治疗，研究主题为“急性肺炎中四萜醇与四环素的比较临床研究”；164例流感后病毒-细菌性肺炎患者，于1972/1973年流感流行期间接受治疗；445例患者于1967 - 1972年在索非亚治疗诊所接受治疗）。总体结果显示，根据所采用的客观指标，四萜醇的治疗效果在统计学上显著优于四环素。还报告了在治疗14例亚急性细菌性心内膜炎患者中获得的有益结果。讨论了这种被定义为“临床协同作用”的优越效果的机制。
