Belovezhdov N, Usheva R
Vutr Boles. 1976;15(1):51-9.
The results from the treatment of 1086 patients, treated at the Therapeutic Clinic, HMI- Sofia were followed up for the period 1961-1970 incld. Acute bacterial and vuris-bacterial pneumonias were found in 318 patients, 475 of the patients were with exacerbated chronic bronchitis and bronchiectasis, with exacerbated chronic pyelo-nephritis -216 patients and with exacerbated chronic cholecystitis and cholangiohepatitis --92 patients. The effect of the treatment was determined according to a three-stage scale "good" with complete clinical healing (in acute pneumonia), with "improvement"--with complete clinical remission (in chronic infections) and "without effect". Clinical and paraclinical indices were used as criteria in the determination of the effectiveness. The data are statistically processed according to the method of variation analysis. In patients with acute pneumonia the- best effectiveness was manifested by tetraolean (88,7 per cent), tetracylins (77,8 per cent), chloramphenicol (76,8 per cent), penicillin (72,5 per cent), the combination penicillin-streptomycin (71,9 per cent); in patients with exacerbated chronic bronchitis--tetraolean (88,0 per cent), chloramphenicol (73,2 per cent), tetracylins (65,3 per cent); in patients with exacerbated chronic pyelonephritis - chloramphenicol (65,5 per cent); in patients with exacerbated chronic cholecystitis and cholecysto-cholangiohepatitis-tetraolean (70,7 per cent), tetracyclins (66,7 per cent), chloramphenicol (66,1 per cent).
对在索非亚市卫生与微生物学研究所治疗诊所接受治疗的1086例患者的治疗结果进行了1961年至1970年期间（含）的随访。其中，318例患者患有急性细菌性和病毒 - 细菌性肺炎，475例患者患有慢性支气管炎和支气管扩张症急性加重，216例患者患有慢性肾盂肾炎急性加重，92例患者患有慢性胆囊炎和胆源性肝炎急性加重。治疗效果根据“良好”（急性肺炎完全临床治愈）、“改善”（慢性感染完全临床缓解）和“无效”三个阶段的标准来确定。在确定疗效时，使用临床和辅助临床指标作为标准。数据采用方差分析方法进行统计学处理。在急性肺炎患者中，齐墩果酸（88.7%）、四环素（77.8%）、氯霉素（76.8%）、青霉素（72.5%）、青霉素 - 链霉素联合用药（71.9%）的疗效最佳；在慢性支气管炎急性加重患者中，齐墩果酸（88.0%）、氯霉素（73.2%）、四环素（65.3%）疗效较好；在慢性肾盂肾炎急性加重患者中，氯霉素（65.5%）疗效较好；在慢性胆囊炎和胆源性肝炎急性加重患者中，齐墩果酸（70.7%）、四环素（66.7%）、氯霉素（66.1%）疗效较好。
