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流感嗜血杆菌的血清型及抗菌药敏性

Serotypes and antimicrobial susceptibility of Haemophilus influenzae.

作者信息

Hussey G, Hitchcock J, Hanslo D, Coetzee G, Van Schalkwyk E, Pitout J, Schaaf H

机构信息

Department of Paediatrics and Child Health, University of Cape Town, Somerset Hospital, Republic of South Africa.

出版信息

J Antimicrob Chemother. 1994 Dec;34(6):1031-6. doi: 10.1093/jac/34.6.1031.

DOI:10.1093/jac/34.6.1031
PMID:7730217
Abstract

During a one year prospective study of Haemophilus influenzae infections in patients treated in hospitals in the metropolitan area of Cape Town. H. influenzae type b accounted for 81.7% of 126 invasive isolates, whereas 86.1% of the 280 non-invasive isolates were non-typeable. Ampicillin resistance was detected among 10.8% of strains of which all but one produced beta-lactamase. All strains were susceptible to cefotaxime as were more than 95% to chloramphenicol, rifampicin, tetracycline but 20.4% were resistant to co-trimoxazole and 87.2% to erythromycin.

摘要

在一项对开普敦大都市区医院治疗的患者中流感嗜血杆菌感染进行的为期一年的前瞻性研究中。b型流感嗜血杆菌占126株侵袭性分离株的81.7%,而280株非侵袭性分离株中有86.1%无法分型。在10.8%的菌株中检测到氨苄西林耐药,其中除一株外均产生β-内酰胺酶。所有菌株对头孢噻肟敏感,对氯霉素、利福平、四环素的敏感率超过95%,但对复方新诺明的耐药率为20.4%,对红霉素的耐药率为87.2%。

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