[婴儿期侵袭性B型流感嗜血杆菌感染（1981 - 1990年）]

[Invasive Haemophilus influenzae type B infections in infancy (1981-1990)].

作者信息

de Juan Martín F, Campos Calleja C, Bustillo Alonso M, Baldovín Ballesteros I, Bello Andrés E, Elviro Mayoral L

机构信息

Sección de Infecciosos, Hospital Infantil Miguel Servet, Zaragoza.

出版信息

An Esp Pediatr. 1993 Aug;39(2):111-5.

PMID:8239205

Abstract

We report the epidemiology of invasive Haemophilus influenzae type B infections. The study is based on 58 children and was carried out during the years from 1981 to 1990. Sixty-three percent of the patients had meningitis, 10.3% had arthritis, 10.3% had epiglottitis, 8.6% had cellulitis and 6.9% had pneumonia. Thirteen percent of the cases were children who were less than 6 months old, 34.4% were less than 12 months old, 70.6% were less than 24 months of age and 93% were less than 4 years old. Among the latter, 90% of the children with epiglottis or pneumonia were 24 months or older compared with 16% of the patients with meningitis, arthritis or cellulitis (p < 0.001). Sixty-three percent of the isolated strains of Haemophilus influenzae type B were resistant to ampicillin and 19.2% of the strains were resistant to ampicillin and chloramphenicol.

摘要

我们报告了B型流感嗜血杆菌侵袭性感染的流行病学情况。该研究基于58名儿童，于1981年至1990年期间开展。63%的患者患有脑膜炎，10.3%患有关节炎，10.3%患有会厌炎，8.6%患有蜂窝织炎，6.9%患有肺炎。13%的病例为6个月以下儿童，34.4%为12个月以下儿童，70.6%为24个月以下儿童，93%为4岁以下儿童。在后者中，90%患有会厌炎或肺炎的儿童年龄在24个月及以上，而患有脑膜炎、关节炎或蜂窝织炎的患者中这一比例为16%（p<0.001）。63%的B型流感嗜血杆菌分离菌株对氨苄西林耐药，19.2%的菌株对氨苄西林和氯霉素耐药。