Glover J, Dibble S L, Dodd M J, Miaskowski C
James Cancer Hospital, Columbus, Ohio, USA.
J Pain Symptom Manage. 1995 Feb;10(2):120-8. doi: 10.1016/0885-3924(94)00073-t.
The purposes of this study were to determine if there were significant differences in the mood states of oncology outpatients who had cancer-related pain and those who were pain free, and to evaluate the relationships between pain intensity and duration and mood states in those patients with pain. Two hundred (54.2%) patients experienced cancer-related pain during the previous month and 169 (45.8%) patients were pain free. Those patients who experienced cancer-related pain scored significantly higher on all of the subscale scores of the Profile of Mood States, except vigor, and had a significantly higher total mood disturbance (TMD) score than did pain-free patients. In addition, the subscale scores of tension, depression, anger, fatigue, confusion, and TMD scores were moderately correlated with increases in pain intensity. Also, depression, fatigue, confusion, and TMD scores were moderately correlated with increasing duration of pain. These data suggest that there is a relationship between pain and mood in oncology outpatients and that health-care professionals need to assess for mood disturbances in this population and develop appropriate treatment strategies.
本研究的目的是确定患有癌症相关疼痛的肿瘤门诊患者与无疼痛患者的情绪状态是否存在显著差异，并评估疼痛强度和持续时间与那些有疼痛患者的情绪状态之间的关系。200名（54.2%）患者在前一个月经历了癌症相关疼痛，169名（45.8%）患者无疼痛。那些经历癌症相关疼痛的患者在情绪状态剖面图的所有子量表得分上，除活力外，均显著更高，且其总情绪紊乱（TMD）得分显著高于无疼痛患者。此外，紧张、抑郁、愤怒、疲劳、困惑的子量表得分以及TMD得分与疼痛强度增加呈中度相关。而且，抑郁、疲劳、困惑和TMD得分与疼痛持续时间增加呈中度相关。这些数据表明，肿瘤门诊患者的疼痛与情绪之间存在关联，医疗保健专业人员需要评估该人群的情绪障碍并制定适当的治疗策略。
