Int J Lepr Other Mycobact Dis. 1995 Mar;63(1):48-55.
Preparations of armadillo-derived Mycobacterium leprae used in vaccine trials were analyzed using a combination of morphological, chemical and immunological criteria. When compared to more recent preparations, vaccine lots prepared in 1984 and 1985 were found to contain fewer intact bacilli and lower amounts of M. leprae antigens. These differences may be characteristic of the original preparations, or alternatively, may have arisen during prolonged storage. The early vaccine lots were those used in the recently published Venezuela trial.
使用形态学、化学和免疫学标准相结合的方法，对用于疫苗试验的犰狳源麻风分枝杆菌制剂进行了分析。与最近的制剂相比，发现1984年和1985年制备的疫苗批次中完整杆菌数量较少，麻风分枝杆菌抗原含量较低。这些差异可能是原始制剂的特征，也可能是在长期储存过程中产生的。早期的疫苗批次是最近发表的委内瑞拉试验中使用的批次。
