Neale A V
Department of Family Medicine, Wayne State University School of Medicine, Detroit, MI 48201, USA.
J Clin Epidemiol. 1994 May;47(5):475-83. doi: 10.1016/0895-4356(94)90294-1.
The association of race and marital status with survival during a 10 year period after a breast cancer diagnosis is described. The data for this study were obtained from the Metropolitan Detroit Cancer Surveillance System, a participant in the National Cancer Institute's SEER program. The study sample was 10,778 women (85.6% white and 14.4% black) diagnosed with incident invasive breast cancer between 1973 and 1978. Marital status was significantly associated with race, but had only a weak relationship with length of survival in a multivariate model predicting 10 year survival. However, race was strongly related to survival. African American women were significantly more likely than white women to die from breast cancer after controlling for age at diagnosis, marital status, tumor stage, histologic type, treatment status, and the interaction of age with stage. Ten years after being diagnosed with breast cancer, 38.2% of whites, compared with 33.3% of blacks were still living. These data confirm a body of literature which finds that blacks experience a shorter survival period following a cancer diagnosis than do whites. However, the relationship of marital status to cancer survival is still unclear and needs further study.
本文描述了种族和婚姻状况与乳腺癌诊断后10年生存期之间的关联。本研究的数据来自底特律大都会癌症监测系统，该系统是美国国家癌症研究所监测、流行病学和最终结果（SEER）计划的参与者。研究样本为1973年至1978年间确诊为原发性浸润性乳腺癌的10778名女性（85.6%为白人，14.4%为黑人）。婚姻状况与种族显著相关，但在预测10年生存期的多变量模型中，与生存时长的关系较弱。然而，种族与生存密切相关。在控制了诊断时的年龄、婚姻状况、肿瘤分期、组织学类型、治疗状况以及年龄与分期的相互作用后，非裔美国女性死于乳腺癌的可能性显著高于白人女性。乳腺癌诊断10年后，38.2%的白人仍在世，而黑人的这一比例为33.3%。这些数据证实了一系列文献的发现，即黑人在癌症诊断后的生存期比白人短。然而，婚姻状况与癌症生存之间的关系仍不明确，需要进一步研究。
