Suppr超能文献

[慢性关节痛:并非类风湿关节炎的前驱症状,而是纤维肌痛综合征的一部分]

[Chronic arthralgia: not a precursor of rheumatoid arthritis, but part of fibromyalgia syndrome].

作者信息

Salet A, Haanen H C

机构信息

St. Antonius Ziekenhuis, afd. Interne Geneeskunde en Reumatologie, Nieuwegein.

出版信息

Ned Tijdschr Geneeskd. 1995 Apr 8;139(14):727-30.

PMID:7731469
Abstract

OBJECTIVE

To determine the characteristics and the course of chronic arthralgia (CA) and the differences from newly diagnosed rheumatoid arthritis (RA).

DESIGN

Retrospective, with a follow up after 2.5 years.

SETTING

Outpatient clinic for rheumatology of the St. Antonius Hospital, Nieuwegein, The Netherlands.

METHOD

The diagnosis of CA was made in the period of June 1986-December 1988 in 74 patients. The CA patients were sent a questionnaire after a mean of 2.5 years and invited for another rheumatological examination; 62 patients responded (84%). Data were compared with all 52 RA patients newly diagnosed in the same period by the same specialist.

RESULTS

At the first visit CA had been present for 1 year, RA patients had had complaints for 0.6 years (p = 0.02). The RA patients had elevated BSE rates more often (31 vs. 8 mm in CA) (p < 0.0001) and more serious morning stiffness (75 vs. 0 minutes in CA) (p < 0.0001). The diagnosis of RA was made at the first visit in 86% and in 96% within half a year later. None of the CA patients developed an inflammatory joint disease within 2.5 years. In 1 out of 3 CA patients the diagnosis of fibromyalgia was made and more than 50% had complaints.

CONCLUSIONS

CA for more than 3 years does not predict inflammatory rheumatic disease. In contrast, RA develops in a short period and the diagnosis is made in 96% within 1 year. CA can be considered a feature of the fibromyalgia syndrome.

摘要

目的

确定慢性关节痛(CA)的特征、病程及其与新诊断类风湿关节炎(RA)的差异。

设计

回顾性研究,随访2.5年。

地点

荷兰新韦根圣安东尼医院风湿病门诊。

方法

1986年6月至1988年12月期间,74例患者被诊断为CA。平均2.5年后,向CA患者发送问卷,并邀请其再次进行风湿病检查;62例患者回复(84%)。将数据与同期由同一位专科医生新诊断的52例RA患者进行比较。

结果

首次就诊时,CA已存在1年,RA患者有症状0.6年(p = 0.02)。RA患者血沉升高更常见(CA组为8 mm,RA组为31 mm)(p < 0.0001),晨僵更严重(CA组为0分钟,RA组为75分钟)(p < 0.0001)。86%的RA患者在首次就诊时被诊断,96%在半年内被诊断。2.5年内,无CA患者发展为炎性关节病。3例CA患者中有1例被诊断为纤维肌痛,超过50%有症状。

结论

超过3年的CA不能预测炎性风湿性疾病。相比之下,RA在短时间内发病,96%在1年内被诊断。CA可被视为纤维肌痛综合征的一个特征。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验