Pozzati E, Andreoli A, Padovani R, Nuzzo G
Division of Neurosurgery, Bellaria Hospital, Bologna, Italy.
Neurosurgery. 1995 Feb;36(2):254-8. doi: 10.1227/00006123-199502000-00003.
Ten patients (six men and four women; mean age, 40 yr) with spontaneous dissection of the basilar artery are reported. Clinically, six were admitted with subarachnoid hemorrhage (SAH) and four were admitted with brain stem ischemia. Angiography demonstrated string sign in four patients, pearl reaction in four, double lumen in one, and arterial ectasia with mural retention of contrast medium in one. Magnetic resonance imaging was performed in two patients. Follow-up angiograms or magnetic resonance angiography in six patients showed spontaneous healing in two patients, improvement in two, progression in one, and no change in one. Nine patients were treated medically, and one underwent selective intravascular occlusion of the dissecting aneurysm. One patient died after further SAH, two remain severely disabled, three have residual neurological deficit, and four are in good clinical condition. The most interesting observations in this series include a relatively good course in a substantial number of patients and low further bleeding potential after SAH, the late "globular" evolution, which may be favorable for reconstructive treatment, and the diagnostic value of associated computed tomographic/angiographic findings. Surgical options in basilar dissection are very poor; in some reported cases, wrapping has been tried with disappointing results. In light of the possibility of spontaneous healing or improvement, wrapping should be reserved for only those patients with recurrent SAH or angiographic progression of the dissection.
本文报告了10例基底动脉自发性夹层患者(6例男性,4例女性;平均年龄40岁)。临床上,6例因蛛网膜下腔出血(SAH)入院,4例因脑干缺血入院。血管造影显示,4例患者出现串珠征,4例出现珍珠反应,1例出现双腔,1例出现动脉扩张伴造影剂壁内潴留。2例患者进行了磁共振成像检查。6例患者的随访血管造影或磁共振血管造影显示,2例患者自发愈合,2例改善,1例进展,1例无变化。9例患者接受了药物治疗,1例患者对夹层动脉瘤进行了选择性血管内栓塞。1例患者在再次发生SAH后死亡,2例仍严重残疾,3例有残留神经功能缺损,4例临床状况良好。该系列中最有趣的观察结果包括,相当一部分患者病程相对良好,SAH后再次出血的可能性较低;后期出现的“球状”演变,可能有利于重建治疗;以及相关计算机断层扫描/血管造影结果的诊断价值。基底动脉夹层的手术选择非常有限;在一些报道的病例中,尝试过包裹术,但结果令人失望。鉴于存在自发愈合或改善的可能性,包裹术应仅用于那些反复发生SAH或夹层在血管造影上有进展的患者。