Sigal L H
University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, New Brunswick, USA.
Rheum Dis Clin North Am. 1995 Feb;21(1):217-30.
Lyme disease has become a major public health problem. One result of this anxiety is over-diagnosis and over-treatment in many endemic and near-to-endemic areas. The diagnosis of Lyme disease is often made solely on the basis of often misinterpreted serologic tests. Therefore, a major reason for inadequate response to antibiotic therapy is initial misdiagnosis. Persisting inflammation and tissue damage following treated Lyme disease does occur but is probably an uncommon cause of refractory symptoms and long-term debility post-Lyme disease.
莱姆病已成为一个主要的公共卫生问题。这种焦虑的一个后果是在许多流行和接近流行的地区存在过度诊断和过度治疗的情况。莱姆病的诊断往往仅基于常常被误解的血清学检测。因此，抗生素治疗反应不佳的一个主要原因是最初的误诊。治疗后的莱姆病确实会出现持续的炎症和组织损伤，但这可能不是莱姆病后难治性症状和长期虚弱的常见原因。
