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[儿童福利院工作人员中乙肝血清学标志物的流行情况]

[Prevalence of Hepatitis B serologic markers among the personnel of the institution for children with deficiencies].

作者信息

Arnedo Pena A, Cortés Edo J M, Latorre Ibáñez M D, González Morán F, Bellido Blasco J B, Querol San Juan J, Guillén Grima F, Safont Adsuara L, Calvo Mas C, Monparler Carrasco P

机构信息

Sección de Epidemiología, Dirección Territorial de Sanidad de Castellón.

出版信息

Rev Sanid Hig Publica (Madr). 1993 May-Jun;67(3):191-200.

PMID:7732285
Abstract

BACKGROUND

The risk of infection by the hepatitis B virus (HBV) in institutions for children with deficiencies has been established in several studies. The purpose of this work was to know the prevalence of HBV markers, among the employees in an institution of that kind, and its association with several risk factors.

METHODS

A transveral epidemiologic survey has been carried out to determine the markers prevalence of infection by hepatitis B virus (HBV) and its association with certain risk factors, among the 200 workers of an institution for children with deficiencies. Determinations, by radioimmunoassay were: HBs Ag, anti-HBs and anti HBe.

RESULTS

The participation was 95%, with a prevalence of any marker of 7.9% (IC95 + 4.1-11.7). No HBs Ag carriers were detected, taking occupation as an indicator variable with three categories: Trades and auxiliary health personnel versus teachers, the logistic regression analysis showed odds ratios, adjusted for age, sex and working time, for trades and auxiliary health personnel, respectively.

CONCLUSIONS

Vaccination is the preventive recommendation for HBV in these institutions, because of the difficulty to find other factors associated to HBV. The possibility of introducing a universal vaccination is controversial.

摘要

背景

多项研究已证实,在残疾儿童机构中,乙型肝炎病毒(HBV)感染风险存在。本研究旨在了解此类机构员工中HBV标志物的流行情况及其与多种风险因素的关联。

方法

对一家残疾儿童机构的200名工作人员进行了横断面流行病学调查,以确定乙型肝炎病毒(HBV)感染标志物的流行情况及其与某些风险因素的关联。通过放射免疫分析法测定:HBs Ag、抗-HBs和抗-HBe。

结果

参与率为95%,任何标志物的流行率为7.9%(95%置信区间为4.1 - 11.7)。未检测到HBs Ag携带者,将职业作为具有三个类别的指示变量: trades和辅助卫生人员与教师相比,逻辑回归分析显示,在调整年龄、性别和工作时间后,trades和辅助卫生人员的优势比分别为……

结论

由于难以找到与HBV相关的其他因素,接种疫苗是这些机构预防HBV的建议措施。引入普遍接种疫苗的可能性存在争议。

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