Brodkey J A, Brodkey J S, Watridge C B
Department of Neurosurgery, University of Tennessee, College of Medicine, Memphis, USA.
Spine (Phila Pa 1976). 1995 Feb 1;20(3):367-72. doi: 10.1097/00007632-199502000-00021.
Paragangliomas are neoplasms that arise from the autonomic nervous system-associated paraganglia. Most often they are benign tumors. However, infrequently they have been reported to metastasize. Involvement of the spine is rare and usually is intradural at the level of the cauda equina.
The authors report two cases of metastatic paraganglioma to the spine, both of which resulted in myelopathy from extradural spinal cord compression. Also provided is a review of the literature.
Paragangliomas rarely metastasize to the spine. Management of the two reported patients involved spinal cord decompression followed by spinal stabilization procedures. Long-term ambulatory status was maintained in both patients. Radiation therapy may be an important adjunctive treatment after surgical removal of these tumors.
副神经节瘤是起源于自主神经系统相关副神经节的肿瘤。它们大多是良性肿瘤。然而，据报道，它们很少发生转移。脊柱受累罕见，通常发生在马尾水平的硬膜内。
作者报告了两例副神经节瘤转移至脊柱的病例，均因硬膜外脊髓受压导致脊髓病。同时还提供了文献综述。
副神经节瘤很少转移至脊柱。所报告的两名患者的治疗包括脊髓减压，随后进行脊柱稳定手术。两名患者均维持了长期行走状态。放射治疗可能是手术切除这些肿瘤后的重要辅助治疗。
