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在心跳骤停的尸体器官供体中对肝脏进行原位分割,以供两名受者移植。

In situ splitting of the liver in the heart-beating cadaveric organ donor for transplantation in two recipients.

作者信息

Rogiers X, Malago M, Habib N, Knoefel W T, Pothmann W, Burdelski M, Meyer-Moldenhauer W H, Broelsch C E

机构信息

Department of Surgery, University Hospital Eppendorf, Hamburg, Germany.

出版信息

Transplantation. 1995 Apr 27;59(8):1081-3.

PMID:7732550
Abstract

SLT presents an interesting concept to alleviate the organ shortage for children with end-stage liver disease. The procedure has, however, not gained wide acceptance. This is not only related to the complexity of the procedure, but also to the poorer results and the complications reported on the right side graft. We report on a first case in which we applied a new concept for splitting. The liver was split in situ in the heart-beating cadaveric donor with the aim of reducing the problems with the right side graft. This procedure makes splitting of the liver possible without submitting the recipient of the right side to increased risk. Therefore, in situ splitting of the liver has the potential of making splitting of liver grafts the rule rather than the exception, thus increasing the organ pool for small children presently carrying a high risk of dying on the waiting list.

摘要

劈离式肝移植(SLT)为缓解终末期肝病患儿的器官短缺问题提出了一个有趣的概念。然而,该手术尚未得到广泛认可。这不仅与手术的复杂性有关,还与右侧供肝的较差结果及并发症有关。我们报告首例应用新劈离概念的病例。在心跳骤停的尸体供体中对肝脏进行原位劈离,目的是减少右侧供肝的问题。该手术使得肝脏劈离成为可能,而不会增加右侧供肝受者的风险。因此,肝脏原位劈离有可能使肝移植劈离成为常规而非例外情况,从而增加目前在等待名单上面临高死亡风险的幼儿的器官来源。

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