Institute of Organ Transplantation, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.
Front Med. 2011 Mar;5(1):1-7. doi: 10.1007/s11684-010-0105-7. Epub 2011 Mar 17.
Partial liver transplantation, including reducedsize liver transplantation, split liver transplantation, and living donor liver transplantation, has been developed with several innovative techniques because of donor shortage. Reduced-size liver transplantation is based on Couinaud's anatomical classification, benefiting children and small adult recipients but failing to relieve the overall donor shortage. Split liver transplantation provides chances to two or even more recipients when only one liver graft is available. The splitting technique must follow stricter anatomical and physiological criteria either ex situ or in situ to ensure long-term quality. The first and most important issue involving living donor liver transplantation is donor safety. Before surgery, a series of donor evaluations-including anatomical, liver volume, and liver function evaluations-is indispensable, followed by ethnic agreement. At different recipient conditions, auxiliary liver transplantation and auxiliary partial orthotopic liver transplantation, which employ piggyback techniques, are good alternatives. Partial liver transplantation enriches the practice and knowledge of the transplant society.
由于供体短缺,部分肝移植(包括小体积肝移植、劈裂肝移植和活体肝移植)已经发展出了多种创新技术。小体积肝移植基于 Couinaud 的解剖分类,有利于儿童和小体型成年受者,但无法缓解整体供体短缺的情况。当只有一个肝移植物时,劈裂肝移植为两个甚至更多受者提供了机会。劈裂技术无论是离体还是原位,都必须遵循更严格的解剖和生理标准,以确保长期质量。涉及活体肝移植的首要和最重要的问题是供者安全。手术前,包括解剖学、肝体积和肝功能评估在内的一系列供者评估是必不可少的,然后是种族协议。在不同的受者条件下,采用背驮式技术的辅助性肝移植和辅助性部分原位肝移植是很好的替代方法。部分肝移植丰富了移植学界的实践和知识。