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部分肝移植。

Partial liver transplantation.

机构信息

Institute of Organ Transplantation, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.

出版信息

Front Med. 2011 Mar;5(1):1-7. doi: 10.1007/s11684-010-0105-7. Epub 2011 Mar 17.

DOI:10.1007/s11684-010-0105-7
PMID:21681668
Abstract

Partial liver transplantation, including reducedsize liver transplantation, split liver transplantation, and living donor liver transplantation, has been developed with several innovative techniques because of donor shortage. Reduced-size liver transplantation is based on Couinaud's anatomical classification, benefiting children and small adult recipients but failing to relieve the overall donor shortage. Split liver transplantation provides chances to two or even more recipients when only one liver graft is available. The splitting technique must follow stricter anatomical and physiological criteria either ex situ or in situ to ensure long-term quality. The first and most important issue involving living donor liver transplantation is donor safety. Before surgery, a series of donor evaluations-including anatomical, liver volume, and liver function evaluations-is indispensable, followed by ethnic agreement. At different recipient conditions, auxiliary liver transplantation and auxiliary partial orthotopic liver transplantation, which employ piggyback techniques, are good alternatives. Partial liver transplantation enriches the practice and knowledge of the transplant society.

摘要

由于供体短缺,部分肝移植(包括小体积肝移植、劈裂肝移植和活体肝移植)已经发展出了多种创新技术。小体积肝移植基于 Couinaud 的解剖分类,有利于儿童和小体型成年受者,但无法缓解整体供体短缺的情况。当只有一个肝移植物时,劈裂肝移植为两个甚至更多受者提供了机会。劈裂技术无论是离体还是原位,都必须遵循更严格的解剖和生理标准,以确保长期质量。涉及活体肝移植的首要和最重要的问题是供者安全。手术前,包括解剖学、肝体积和肝功能评估在内的一系列供者评估是必不可少的,然后是种族协议。在不同的受者条件下,采用背驮式技术的辅助性肝移植和辅助性部分原位肝移植是很好的替代方法。部分肝移植丰富了移植学界的实践和知识。

相似文献

1
Partial liver transplantation.部分肝移植。
Front Med. 2011 Mar;5(1):1-7. doi: 10.1007/s11684-010-0105-7. Epub 2011 Mar 17.
2
In situ splitting of the cadaveric liver for transplantation.尸体肝脏原位劈裂用于移植。
Transplantation. 1997 Sep 27;64(6):871-7. doi: 10.1097/00007890-199709270-00014.
3
Split liver transplantation: a reliable approach to expand donor pool.活体肝移植:扩大供体库的可靠方法。
Hepatobiliary Pancreat Dis Int. 2005 Aug;4(3):339-44.
4
Reduced size liver transplantation, split liver transplantation, and living related liver transplantation in relation to the donor organ shortage.与供体器官短缺相关的减体积肝移植、劈离式肝移植和活体亲属肝移植。
Transpl Int. 1995;8(1):65-8. doi: 10.1007/BF00366715.
5
Split liver transplantation.劈离式肝移植
Ann Surg. 1999 Mar;229(3):313-21. doi: 10.1097/00000658-199903000-00003.
6
Needs must: living donor liver transplantation from an HIV-positive mother to her HIV-negative child in Johannesburg, South Africa.需要:在南非约翰内斯堡,一名 HIV 阳性母亲向其 HIV 阴性孩子进行活体供肝移植。
J Med Ethics. 2019 May;45(5):287-290. doi: 10.1136/medethics-2018-105216.
7
[Living Donor Liver Transplantation - Past and Present].[活体肝移植——过去与现在]
Zentralbl Chir. 2016 Oct;141(5):559-564. doi: 10.1055/s-0032-1328347. Epub 2013 Jul 3.
8
In situ splitting of the cadaveric liver for two adult recipients.将尸体肝脏原位分割给两名成年受者。
Transplantation. 2001 Dec 15;72(11):1853-8. doi: 10.1097/00007890-200112150-00028.
9
Split-liver transplantation: a comparison of ex vivo and in situ techniques.劈离式肝移植:体外与原位技术的比较
J Pediatr Surg. 2000 Feb;35(2):283-9; discussion 289-90. doi: 10.1016/s0022-3468(00)90026-5.
10
[Strategies for a greater supply of organs for transplantation].[增加移植器官供应的策略]
Recenti Prog Med. 2001 Jan;92(1):9-15.

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本文引用的文献

1
Variant techniques for liver transplantation in pediatric programs.儿科项目中肝脏移植的变异技术。
Eur J Pediatr Surg. 2008 Dec;18(6):372-4. doi: 10.1055/s-2008-1038900. Epub 2008 Nov 27.
2
Strategies for improving the outcomes of small-for-size grafts in adult-to-adult living-donor liver transplantation.改善成人对成人活体肝移植中小体积移植物预后的策略。
J Hepatobiliary Pancreat Surg. 2008;15(2):102-10. doi: 10.1007/s00534-007-1297-3. Epub 2008 Apr 6.
3
Outcomes of adult-to-adult living donor liver transplantation: a single institution's experience with 335 consecutive cases.
小儿肝脏移植中的原位肝离断及人纤维蛋白原和凝血酶海绵在创面的应用
Arq Bras Cir Dig. 2016 Nov-Dec;29(4):236-239. doi: 10.1590/0102-6720201600040006.
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Postreperfusion syndrome during liver transplantation.肝移植术中的再灌注综合征
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5
Retrospective observation of therapeutic effects of adult auxiliary partial living donor liver transplantation on postpartum acute liver failure: a case report.成人辅助性部分活体供肝移植治疗产后急性肝衰竭疗效的回顾性观察:1例病例报告
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End-to-side caval anastomosis in adult piggyback liver transplantation.成年背驮式肝移植中的腔静脉端侧吻合术。
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Improved survival after live donor adult liver transplantation (LDALT) using right lobe grafts: program experience and lessons learned.使用右叶移植物的活体供体成人肝移植(LDALT)术后生存率提高:项目经验与教训
Am J Transplant. 2006 Mar;6(3):589-98. doi: 10.1111/j.1600-6143.2005.01220.x.
6
Triangular and self-triangulating cavocavostomy for orthotopic liver transplantation without posterior suture lines: a modified surgical technique.
Transpl Int. 2006 Feb;19(2):117-21. doi: 10.1111/j.1432-2277.2005.00246.x.
7
Current role of liver transplantation for the treatment of urea cycle disorders: a review of the worldwide English literature and 13 cases at Kyoto University.肝移植在尿素循环障碍治疗中的当前作用:对全球英文文献及京都大学13例病例的综述
Liver Transpl. 2005 Nov;11(11):1332-42. doi: 10.1002/lt.20587.
8
Analysis and outcomes of right lobe hepatectomy in 101 consecutive living donors.101例连续活体供者右半肝切除术的分析及结果
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9
Small-for-size syndrome after partial liver transplantation: definition, mechanisms of disease and clinical implications.部分肝移植后的小体积综合征:定义、发病机制及临床意义
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10
Cadaveric orthotopic auxiliary split liver transplantation and kidney transplantation: an alternative for type 1 primary hyperoxaluria.尸体原位辅助性劈离肝移植和肾移植:1型原发性高草酸尿症的一种替代治疗方法
Transplantation. 2005 Aug 15;80(3):421-4. doi: 10.1097/01.tp.0000168147.88707.80.