[关于1966年至1973年从患者中分离出的志贺氏菌对抗生素敏感性的观察]

[Observations on the sensitivity to antibiotics of the Shigella isolated from patients in 1966-1973].

作者信息

Garanin B A

出版信息

Antibiotiki. 1975 Jun;20(6):533-7.

Abstract

Sensitivity to levomycetin, streptomycin, chlortetracycline, oxytetracycline, monomycin, neomycin and erythromycin of 3766 strains of Shigella isolated from dysentery patients within 1966-1973 was determined with the method of standard discs. The strains proved to be resistant to tetracycline (94.3-99.4 per cent), streptomycin (85.1-94.9 per cent) and levomycetin (69-93.1 percent). By present the dysentery bacilli have preserved their sensitivity to monomycin (88.2 per cent) and neomycin (98.2 per cent). Cultures insensitive or slightly sensitive to erythromycin predominated. Strains with multiple resistance amounted to 79 per cent, including 82.5 per cent of Shigella Sonne, 51.8 per cent of Shigella Flexneri and 35.9 percent of Newcastle bacteria.

摘要

采用标准纸片法测定了1966年至1973年期间从痢疾患者分离出的3766株志贺氏菌对氯霉素、链霉素、金霉素、土霉素、新生霉素、新霉素和红霉素的敏感性。结果表明，这些菌株对四环素（94.3% - 99.4%）、链霉素（85.1% - 94.9%）和氯霉素（69% - 93.1%）耐药。目前痢疾杆菌对新生霉素（88.2%）和新霉素（98.2%）仍保持敏感。对红霉素不敏感或轻度敏感的培养物占多数。多重耐药菌株占79%，其中宋内氏志贺氏菌占82.5%，福氏志贺氏菌占51.8%，鲍氏志贺氏菌占35.9%。