Furuya K, Kubo T, Shoda S, Kawano S, Kubota N
Department of Ophthalmology, Teikyo University School of Medicine, Tokyo, Japan.
Nippon Ganka Gakkai Zasshi. 1995 Mar;99(3):349-57.
We recorded pattern-reversal visual evoked potentials (P-VEP) from dissociated vertical deviation (DVD) patients to evaluate the sensory system abnormalities in DVD. 91 DVD patients with good visual acuity were studied. Normal subjects and horizontal strabismic patients without DVD were compared for evaluation. Transient and steady state P-VEPs were recorded from three EEG electrodes placed on the posterior scalp. Half-field checker-board reversal stimulation was applied to stimulate monocular temporal retina and responses from right and left hemispheres were also compared for evaluation. Paradoxical lateralization was observed in all normal subjects. Abnormal P-VEPs were observed in 4 of 20 (20%) horizontal strabismic patients without DVD when employing the transient stimulation method and in 2 of 8 (25%) when using steady state stimulation. Abnormal P-VEPs were observed in 31 of 67 (46.3%) DVD patients, with the transient stimulation method and in 20 of 25 (80.0%) DVD patients with the steady state stimulation method. The abnormalities were various and diverse. Our observations indicate that DVD patients frequently have an abnormal sensory system detected by P-VEP, and DVD might be a complex and multi-origin condition involving both sensory and motor systems.
我们记录了分离性垂直偏斜（DVD）患者的图形翻转视觉诱发电位（P-VEP），以评估DVD患者的感觉系统异常情况。对91例视力良好的DVD患者进行了研究。将其与正常受试者以及无DVD的水平斜视患者进行比较以作评估。从放置于头皮后部的三个脑电图电极记录瞬态和稳态P-VEP。应用半视野棋盘格翻转刺激来刺激单眼颞侧视网膜，并比较左右半球的反应以作评估。在所有正常受试者中均观察到了矛盾性偏侧化。在无DVD的20例水平斜视患者中，采用瞬态刺激方法时有4例（20%）观察到P-VEP异常，采用稳态刺激方法时8例中有2例（25%）观察到异常。在67例DVD患者中，采用瞬态刺激方法时有31例（46.3%）观察到P-VEP异常，采用稳态刺激方法时25例中有20例（80.0%）观察到异常。这些异常情况多种多样。我们的观察结果表明，DVD患者经常通过P-VEP检测出感觉系统异常，并且DVD可能是一种涉及感觉和运动系统的复杂且多源性病症。
