年轻孕产妇年龄与先天性畸形：一项基于人群的研究。
Young maternal age and congenital malformations: a population-based study.
作者信息
Croen L A, Shaw G M
机构信息
March of Dimes Birth Defects Foundation, Emeryville, Calif, USA.
出版信息
Am J Public Health. 1995 May;85(5):710-3. doi: 10.2105/ajph.85.5.710.
Abstract
This study examined the prevalence of congenital malformations across the maternal age spectrum and identified specific malformation types that contributed to the overall prevalence among mothers under the age of 20 years. Data were derived from the California Birth Defects Monitoring Program for 1983 through 1988 live births. The distribution of prevalences of all nonchromosomal malformations was U-shaped across maternal age. Furthermore, several specific malformation types, representing nearly every organ system, were elevated among the infants of women under 20 years of age in comparison with those of women 25 to 29 years old.
摘要
本研究调查了不同年龄段母亲中先天性畸形的患病率，并确定了导致20岁以下母亲总体患病率的特定畸形类型。数据来源于加利福尼亚出生缺陷监测项目1983年至1988年的活产记录。所有非染色体畸形的患病率分布在母亲年龄上呈U形。此外，与25至29岁的女性相比，20岁以下女性所生婴儿中，几乎代表每个器官系统的几种特定畸形类型的患病率有所升高。
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