Fetu D, Carel N, Fossier T, Motreff C
Service d'Anesthésie-Réanimation, Centre Hospitalier, Pontivy.
Ann Fr Anesth Reanim. 1994;13(5):745-8. doi: 10.1016/s0750-7658(05)80735-x.
The intentional ingestion of 5 g of chloral hydrate by a 67-yr-old man resulted in cardiac arrhythmia including tachyarrhythmia and polymorphic ventricular extrasystoles. As the ingested agent was unknown at admission, the patient was treated among others with sodium lactate, a non validated therapy of arrhythmia caused by chloral hydrate overdose. The discontinuation of arrhythmia was in favour of a beneficial effect of this treatment which remains to be confirmed. This unusual therapy is the original point of this case report which allows to question the so-called innocuousness of chloral hydrate, to remind the conventional treatment of the arrhythmias caused by this agent, the place of beta-adrenergic blockers, as well as the therapeutic difficulties when the causative agent remains unknown.
一名67岁男性故意摄入5克水合氯醛，导致心律失常，包括快速性心律失常和多形性室性期前收缩。由于入院时摄入的药物不明，患者接受了多种治疗，包括乳酸钠治疗，这是一种未经证实的治疗水合氯醛过量所致心律失常的方法。心律失常的终止有利于这种治疗的有益效果，但仍有待证实。这种不寻常的治疗方法是本病例报告的独特之处，它促使人们质疑水合氯醛所谓的无害性，提醒人们注意这种药物所致心律失常的常规治疗方法、β肾上腺素能阻滞剂的作用，以及在致病药物不明时的治疗困难。
