Gustafson A, Svensson S E, Ugander L
Acta Med Scand. 1977;201(3):227-30. doi: 10.1111/j.0954-6820.1977.tb15687.x.
In three patients admitted to hospital after ingestion of an overdose of chloral hydrate, the ECG showed supreventricular and ventricular tachyarrhythmias. The possible mechanism for the arrhythmias may be an enhanced automaticity of supraventricular and ventricular pacemaker cells caused by metabolites of chloral hydrate. The ventricular arrhythmia responded to i.v. treatment with lignocaine in one patient, and to phenytoin in another in whom lignocaine failed to restore a normal sinus rhythm.
三名因过量服用水合氯醛入院的患者，其心电图显示有室上性和室性快速心律失常。心律失常的可能机制可能是水合氯醛的代谢产物导致室上性和室性起搏细胞的自律性增强。一名患者的室性心律失常经静脉注射利多卡因治疗有效，另一名患者利多卡因未能恢复正常窦性心律，改用苯妥英钠治疗有效。
