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胸部巨大淋巴结增生症(卡斯尔曼病)

Giant lymph node hyperplasia (Castleman's disease) in the chest.

作者信息

Kim J H, Jun T G, Sung S W, Shim Y S, Han S K, Kim Y W, Yoo C G, Seo J W, Rho J R

机构信息

Department of Thoracic and Cardiovascular Surgery, Seoul National University Hospital, South Korea.

出版信息

Ann Thorac Surg. 1995 May;59(5):1162-5. doi: 10.1016/0003-4975(95)00124-4.

DOI:10.1016/0003-4975(95)00124-4
PMID:7733713
Abstract

We have experienced 7 cases of giant lymph node hyperplasia in the chest from 1981 to 1992. The ages of the 1 male and 6 female patients ranged from 9.9 to 40.4 years (mean age, 29.2 +/- 10.4 years). In 4 patients, a mass was discovered in routine radiographs. Focal calcification suggesting continual enlargement over a long time was noted in 1 patient. The sites of lesions were unusual in 2 patients (intercostal space and intrapulmonary fissure). All patients underwent surgical removal of the mass. Five cases had typical features of the hyaline-vascular type, and 2 cases revealed a mixture of the hyaline-vascular type and the plasma-cell type. Follow-up was available in all patients (mean follow-up, 31.9 months). In 1 patient, recurrence was observed 9 years after surgical removal. In general, giant lymph node hyperplasia can occur anywhere in the chest, grow without symptoms, and recur in spite of complete resection. Surgical resection and close follow-up are advised.

摘要

1981年至1992年期间,我们共收治7例胸部巨大淋巴结增生患者。其中男性1例,女性6例,年龄9.9至40.4岁(平均年龄29.2±10.4岁)。4例患者在常规X线检查时发现肿块。1例患者可见提示长期持续增大的局灶性钙化。2例患者病变部位不常见(肋间隙和肺内裂)。所有患者均接受了肿块切除术。5例具有透明血管型的典型特征,2例表现为透明血管型和浆细胞型混合。所有患者均进行了随访(平均随访31.9个月)。1例患者在手术切除9年后复发。一般来说,巨大淋巴结增生可发生于胸部任何部位,无症状生长,即使完全切除仍可复发。建议手术切除并密切随访。

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