Haro Akira, Kuramitsu Erina, Fukuyama Yasuro
Department of Thoracic Surgery, Nakatsu Municipal Hospital, Nakatsu, Oita, Japan.
Department of Thoracic Surgery, Nakatsu Municipal Hospital, Nakatsu, Oita, Japan.
Int J Surg Case Rep. 2016;25:44-7. doi: 10.1016/j.ijscr.2016.05.053. Epub 2016 Jun 3.
Castleman disease (CD) is a rare benign lymphoproliferative disorder characterized by benign lymph node hyperplasia in a single site (unicentric CD [UCD]) or in multiple sites (multicentric CD [MCD]). Patients with UCD are usually asymptomatic; however, those with MCD usually develop fever, weight loss, and peripheral lymphadenopathy.
We describe a case of surgically resected UCD in the superior mediastinum in which the involved lymph node was surrounded by important vessels and trachea, necessitating a median sternotomy for complete resection of the tumor.
Preoperative diagnosis of UCD in the thorax is very difficult, and surgical resection or excision is necessary. Complete resection is recommended for UCD because it is curative and has a 5-year survival rate of 100%.
UCD should be included in the differential diagnosis of asymptomatic mediastinal tumors. Surgical resection or excision is preferred to ensure an accurate diagnosis and appropriate treatment if malignant disease cannot otherwise be ruled out.
卡斯特曼病（CD）是一种罕见的良性淋巴增生性疾病，其特征为单个部位（单中心CD [UCD]）或多个部位（多中心CD [MCD]）出现良性淋巴结增生。UCD患者通常无症状；然而，MCD患者通常会出现发热、体重减轻和外周淋巴结病。
我们描述了一例位于上纵隔的经手术切除的UCD病例，其中受累淋巴结被重要血管和气管环绕，因此需要进行正中胸骨切开术以完整切除肿瘤。
胸部UCD的术前诊断非常困难，手术切除或摘除是必要的。建议对UCD进行完整切除，因为这是可治愈的且5年生存率为100%。
UCD应纳入无症状纵隔肿瘤的鉴别诊断。如果无法排除恶性疾病，首选手术切除或摘除以确保准确诊断和适当治疗。
