Chua M G, Davis S M, Infeld B, Rossiter S C, Tress B M, Hopper J L
The University, Department of Medicine, Royal Melbourne Hospital, Victoria, Australia.
Arch Neurol. 1995 May;52(5):496-500. doi: 10.1001/archneur.1995.00540290086022.
To compare the acute Allen's Prognostic Score, Canadian Neurological Score, and subacute Barthel Index as predictors of outcome functional status and infarct size at 3 months in patients with acute cortical infarction.
A prospective study of acute stroke predictors and outcome measurements in a cohort of sequential hospitalized patients.
Fifty-one patients with acute cortical infarction and without previous disability assessed 24 hours after onset with Allen's Prognostic Score and the Canadian Neurological Score and at 7 days with the Barthel Index.
Mortality, Barthel Index, and volumetric measurement of infarct size on computed tomography 3 months after stroke.
There were seven deaths. The outcome Barthel Index was measured in all 44 survivors, of whom 29 had computed tomography at the time outcome was determined. In a multivariate analysis, functional outcome was best predicted by Allen's Prognostic Score, a score of less than -15 having a sensitivity of 82% and specificity of 97% in predicting a poor outcome (Barthel Index, < or = 12 or death). Volumetric tissue loss was predicted only by Allen's Prognostic Score (r = .62, P < .001).
Allen's Prognostic Score is a robust predictor of both functional outcome and tissue loss in acute cortical infarction and has a potentially important role in the analysis of the results of acute stroke intervention trials.
比较急性艾伦预后评分、加拿大神经功能评分和亚急性巴氏指数，以预测急性皮质梗死患者3个月时的功能状态和梗死灶大小。
对一系列住院患者进行急性卒中预测因素和预后测量的前瞻性研究。
51例急性皮质梗死患者，既往无残疾，发病24小时后采用艾伦预后评分和加拿大神经功能评分进行评估，7天时采用巴氏指数进行评估。
卒中后3个月的死亡率、巴氏指数以及计算机断层扫描测量的梗死灶体积。
有7例死亡。对所有44例幸存者进行了预后巴氏指数测量，其中29例在确定预后时进行了计算机断层扫描。在多变量分析中，艾伦预后评分对功能预后的预测效果最佳，评分低于-15时，预测不良预后（巴氏指数≤12或死亡）的敏感性为82%，特异性为97%。仅艾伦预后评分可预测组织体积损失（r = 0.62，P < 0.001）。
艾伦预后评分是急性皮质梗死功能预后和组织损失的有力预测指标，在急性卒中干预试验结果分析中可能具有重要作用。
