双嘧达莫与阿司匹林预防术后深静脉血栓形成
Prevention of postoperative deep vein thrombosis with dipyridamole and aspirin.
作者信息
Renney J T, O'Sullivan E F, Burke P F
出版信息
Br Med J. 1976 Apr 24;1(6016):992-4. doi: 10.1136/bmj.1.6016.992.
Abstract
One hundred and sixty patients have been studied in a controlled trial of two drugs which have been in combination to prevent postoperative-deep-vein thrombosis. Both the drugs, dipyridamole (Persantin) and aspirin, were given by mouth from the evening before operation and for seven days after operation. The radioactive fibrinogen test was used to diagnose thrombosis. Of the 85 patients in the control group 24 developed thrombosis (28%). Twelve out of 85 patients (14%) in the test group were found to have thrombosis. Similar significant differences in incidence were found in the various subgroups.
摘要
在一项针对两种联合用药预防术后深静脉血栓形成的对照试验中，对160名患者进行了研究。双嘧达莫（潘生丁）和阿司匹林这两种药物均在手术前一晚开始口服，并在术后服用七天。采用放射性纤维蛋白原试验诊断血栓形成。对照组的85名患者中有24人发生血栓形成（28%）。试验组的85名患者中有12人（14%）被发现有血栓形成。在各个亚组中也发现了类似的显著发病率差异。
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