预防老年髋部骨折患者静脉血栓栓塞：低剂量肝素、双嘧达莫、阿司匹林和氟比洛芬的研究
Preventing venous thromboembolism in elderly patients with hip fractures: studies of low-dose heparin, dipyridamole, aspirin, and flurbiprofen.
作者信息
Morris G K, Mitchell J R
出版信息
Br Med J. 1977 Feb 26;1(6060):535-7. doi: 10.1136/bmj.1.6060.535.
Abstract
Low-dose heparin, dipyridamole (alone and in combination with aspirin), and flurbiprofen were evaluated as potential prophylactic agents against deep venous thrombosis in elderly patients with hip fractures. None of the agents that modify platelet behaviour could reduct the frequency of isotopically diagnosed venous thrombosis. Low-dose heparin reduced the overall frequency of venous thrombosis and its extent as judged by the frequency of bilaterally abnormal scans, but this reduction did not achieve statistical significance.
摘要
低剂量肝素、双嘧达莫（单独使用以及与阿司匹林联合使用）和氟比洛芬被评估为髋部骨折老年患者深静脉血栓形成的潜在预防药物。没有一种改变血小板行为的药物能够降低同位素诊断的静脉血栓形成的发生率。低剂量肝素降低了静脉血栓形成的总体发生率及其程度（通过双侧异常扫描的频率判断），但这种降低未达到统计学显著性。
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