Mygind N
Department of Otorhinolaryngology, Rigshospitalet, Copenhagen, Denmark.
Eur Arch Otorhinolaryngol. 1995;252 Suppl 1:S68-72. doi: 10.1007/BF02484439.
The diagnosis of allergic rhinitis is based on the case history, rhinoscopy and allergy testing. Therapy consists of allergen avoidance, pharmacotherapy, immunotherapy and/or surgery. This review deals only with pharmacotherapy, since there has been significant progress in this area. The first advance was the introduction of topical nasal steroids in the mid-1970s and the second the introduction of the second generation of H1 antihistamines in the early 1980s. The task for future developments is to optimize therapy by rational and combined use of available drugs, especially the steroid sprays and non-sedating antihistamines. A systematic approach to the choice of drug for the treatment of rhinitis is presented.
变应性鼻炎的诊断基于病史、鼻镜检查和变应原检测。治疗方法包括避免接触变应原、药物治疗、免疫治疗和/或手术治疗。本综述仅涉及药物治疗,因为该领域已取得显著进展。第一个进展是20世纪70年代中期引入了局部鼻用类固醇,第二个进展是20世纪80年代初引入了第二代H1抗组胺药。未来发展的任务是通过合理联合使用现有药物,尤其是类固醇喷雾剂和非镇静性抗组胺药来优化治疗。本文介绍了一种系统性的鼻炎治疗药物选择方法。