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全髋关节置换术中髋臼同种异体骨移植重建:临床、X线及骨闪烁显像分析的初步报告

Acetabular allograft reconstruction in total hip arthroplasty: preliminary report with clinical, roentgenographic and scintigraphic analyses.

作者信息

Chen C H, Shih C H

机构信息

Department of Orthopedic Surgery, Chang Gung Memorial Hospital, Chang Gung Medical College, Taipei, Taiwan R.O.C.

出版信息

J Formos Med Assoc. 1994 Sep;93(9):781-7.

PMID:7735008
Abstract

From January 1986 to June 1991, we used structural allografts to augment major acetabular deficiencies during primary or revision total hip arthroplasty (THA) in 54 patients. Forty-four patients (46 hips) with a minimal follow-up of two years were reviewed. The average patient age was 50.2 years. The diagnosis was loose THA component in 36 hips, six failed Austin-Moores, three septic hip sequelae, and one failed bipolar hemiarthroplasty. Their preoperative hip ratings (modified d'Aubigne and Postel rating system) averaged 10.7 points. Forty-five allografts (98%) united roentgenographically with an average union period of 11.8 months. Five acetabular components (10.9%) developed aseptic loosening; one of them underwent revision using a healing allograft and one hip needed further acetabular reconstruction with allograft due to complete necrosis of the original allograft. One additional hip required resection arthroplasty for septic loosening. The 43 surviving hips had a mean hip score of 16.7 points at the latest follow-up. Radiographic evidence of graft resorption was seen in eight hips, which was not correlated with acetabular loosening. Serial single photon emission computed tomography (SPECT) study was employed postoperatively in 20 patients (21 hips) to assess the healing process and graft viability. Seven allografts (33.3%) were nonviable on serial SPECT studies, while 14 allografts (66.7%) were viable. The compatibility of host-donor A, B, O blood typing and the use of cement did not correlate with allograft viability. Allograft viability did not contribute to the failure of cup components. Considering the major acetabular deficiency and the absence of sufficient autograft material, the use of frozen allografts appears to be justified.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

1986年1月至1991年6月,我们在54例初次或翻修全髋关节置换术(THA)中使用结构性同种异体骨移植来增加严重髋臼缺损。对44例患者(46髋)进行了至少两年的随访。患者平均年龄为50.2岁。诊断为THA假体松动36髋,6例Austin-Moore假体失败,3例化脓性髋后遗症,1例双极半髋关节置换失败。术前髋关节评分(改良d'Aubigne和Postel评分系统)平均为10.7分。45例同种异体骨移植(98%)在X线片上愈合,平均愈合时间为11.8个月。5个髋臼假体(10.9%)发生无菌性松动;其中1例使用愈合的同种异体骨进行翻修,1髋因原同种异体骨完全坏死需要进一步用同种异体骨进行髋臼重建。另有1髋因感染性松动需要行切除关节成形术。43例存活髋在最近一次随访时平均髋关节评分为16.7分。8髋可见移植骨吸收的影像学证据,这与髋臼松动无关。20例患者(21髋)术后采用连续单光子发射计算机断层扫描(SPECT)研究来评估愈合过程和移植骨的存活情况。连续SPECT研究显示7例同种异体骨(33.3%)无活性,14例同种异体骨(66.7%)有活性。宿主-供体ABO血型相容性及骨水泥的使用与同种异体骨活性无关。同种异体骨活性与髋臼假体失败无关。考虑到严重的髋臼缺损且缺乏足够的自体骨材料,使用冷冻同种异体骨似乎是合理的。(摘要截短至250字)

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