Scott P R, Sargison N D, Penny C D, Pirie R S, Kelly J M
Department of Veterinary Clinical Studies, Veterinary Field Station, Easter Bush, Roslin, Midlothian, UK.
Br Vet J. 1995 Jan-Feb;151(1):39-44. doi: 10.1016/s0007-1935(05)80063-6.
Cerebrospinal fluid (CSF) and plasma glucose concentrations of spontaneous ovine pregnancy toxaemia cases, determined within 24 h of the onset of clinical signs, were significantly lower (P < 0.01) compared to inappetant ewes and healthy ewes at a similar stage of gestation. A highly significant correlation (P < 0.001, r = 0.91) was present between the plasma and CSF glucose concentrations when the data from the three groups were combined. The data suggest that plasma glucose concentration accurately reflects CSF glucose concentration across the range of energy states in pregnant ewes and may provide support for the postulate that the neurological signs of ovine pregnancy toxaemia result from cerebral hypoglycaemia, as reflected by CSF glucose concentration. No cerebral glucose estimations were undertaken in this series.
在出现临床症状的24小时内测定的自然发生绵羊妊娠毒血症病例的脑脊液（CSF）和血浆葡萄糖浓度，与处于相似妊娠阶段的食欲不振母羊和健康母羊相比，显著更低（P < 0.01）。当将三组数据合并时，血浆和脑脊液葡萄糖浓度之间存在高度显著的相关性（P < 0.001，r = 0.91）。数据表明，血浆葡萄糖浓度准确反映了妊娠母羊整个能量状态范围内的脑脊液葡萄糖浓度，并可能为绵羊妊娠毒血症的神经症状由脑脊液葡萄糖浓度所反映的脑低血糖引起这一假设提供支持。本系列研究未进行脑葡萄糖测定。
