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土霉素二水合物在治疗羔羊支原体相关性羊角膜结膜炎中的作用。

Role of oxytetracycline dihydrate in the treatment of mycoplasma-associated ovine keratoconjunctivitis in lambs.

作者信息

Hosie B D, Greig A

机构信息

SAC Veterinary Services, Greycrook, St Boswells, Roxburghshire, UK.

出版信息

Br Vet J. 1995 Jan-Feb;151(1):83-8. doi: 10.1016/s0007-1935(05)80067-3.

DOI:10.1016/s0007-1935(05)80067-3
PMID:7735873
Abstract

Thirty-six lambs were placed in two groups of 10 each, one group of 11 and one group of five. The first three groups were challenged with a field strain of Mycoplasma conjunctivae and the group of five lambs with an inactivated culture. One group of lambs was treated with oxytetracycline dihydrate as conjunctivitis developed at 1 day post-inoculation (dpi) and the other group was treated when the conjunctivitis was at its most severe (3 dpi). A rapid response to treatment was observed with a complete recovery obtained after 2 and 4 days, respectively. However, the treatment did not eliminate the M. conjunctivae infection. Conjunctivitis did not develop in the five lambs challenged with the inactivated culture.

摘要

36只羔羊被分成四组,其中三组每组10只,一组11只,一组5只。前三组用结膜支原体野毒株攻毒,5只羔羊的那一组用灭活培养物攻毒。一组羔羊在接种后1天(dpi)发生结膜炎时用二水氧四环素治疗,另一组在结膜炎最严重时(3 dpi)治疗。观察到治疗反应迅速,分别在2天和4天后完全恢复。然而,治疗并未消除结膜支原体感染。用灭活培养物攻毒的5只羔羊未发生结膜炎。

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