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在头部损伤中使用颈静脉血氧饱和度测定法评估脑氧合情况。

Evaluating cerebral oxygenation using jugular venous oximetry in head injuries.

作者信息

Kerr M E, Lovasik D, Darby J

出版信息

AACN Clin Issues. 1995 Feb;6(1):11-20. doi: 10.1097/00044067-199502000-00003.

Abstract

When caring for the critically ill patient, a primary objective is to maintain an adequate delivery of oxygen to the tissues. Monitoring and ensuring satisfactory cerebral oxygen delivery in patients at risk for cerebral ischemia presents a significant challenge to the clinician. Cerebral oxygen content usually is determined using blood gas analysis, whereas blood flow to cerebral tissues is inferred from monitoring of the cerebral perfusion pressure. There is an assumption that cerebral oxygen delivery is adequate so long as the cerebral perfusion pressure exceeds 50-60 mmHg in the normal brain and the cerebral arterial oxygen content is normal. The cerebral perfusion pressure, however, is an estimated value calculated as the difference between the mean systemic arterial pressure and the intracranial pressure and provides merely an indirect index of the adequacy of cerebral oxygen delivery. The validity of the cerebral perfusion pressure as an index for cerebral oxygen delivery becomes questionable when the autoregulatory mechanisms of the brain are disturbed, as in severe head injuries. Jugular bulb oxygen monitoring provides a method of evaluating cerebral oxygenation status for early identification of impending ischemia by measuring oxygenation of the mixed cerebral venous blood. In this article, the authors review the physiology of cerebral oxygenation, describe a method of monitoring cerebral oxygenation using jugular bulb oximetry, and review a case study to show how these assessments can affect the nursing care of the head-injured patient.

摘要

在护理重症患者时,首要目标是维持向组织充分输送氧气。对于有脑缺血风险的患者,监测并确保令人满意的脑氧输送对临床医生构成了重大挑战。脑氧含量通常通过血气分析来确定,而脑组织的血流则通过监测脑灌注压来推断。有一种假设认为,只要正常脑的脑灌注压超过50 - 60 mmHg且脑动脉氧含量正常,脑氧输送就是充足的。然而,脑灌注压是通过计算平均体动脉压与颅内压之差得出的估计值,仅仅提供了脑氧输送充足性的间接指标。当大脑的自动调节机制受到干扰时,如在严重头部损伤中,脑灌注压作为脑氧输送指标的有效性就会受到质疑。颈静脉球部氧监测提供了一种通过测量混合脑静脉血的氧合来评估脑氧合状态的方法,以便早期识别即将发生的缺血。在本文中,作者回顾了脑氧合的生理学,描述了一种使用颈静脉球部血氧饱和度测定法监测脑氧合的方法,并回顾了一个案例研究,以展示这些评估如何影响头部受伤患者的护理。

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