De Deyne C, Decruyenaere J, Calle P, Vandekerckhove T, Vaganee B, Blanca Garcia R, Colardyn F
Department of Intensive Care, University Hospital Gent, Belgium.
Eur J Emerg Med. 1996 Jun;3(2):69-72. doi: 10.1097/00063110-199606000-00002.
Jugular bulb oximetry provides the first bedside available information on cerebral oxygen utilization. An extensive analysis was made of all initial jugular bulb oximetry data obtained in 150 patients within the first 12 h after severe traumatic brain injury. These data revealed initial abnormal jugular bulb saturation values in 57 patients (= 38% of study population), with a predominance of jugular bulb desaturation (observed in 45 patients). This confirms earlier reports that revealed a high incidence of disturbed and inadequate cerebral perfusion in the first hours after brain injury. Jugular bulb desaturation was especially related to systemic causes (such as a lowered cerebral perfusion pressure observed in 29 patients, and a lowered arterial carbon dioxide tension in 24 patients). These findings could have important implications for the emergency management of severely head-injured patients, as outcome might possibly be improved by better attention to all systemic factors that might reduce cerebral perfusion in the early hours after traumatic insult.
颈静脉球血氧饱和度测定可提供有关脑氧利用的首个床边可用信息。对150例重度创伤性脑损伤患者在伤后12小时内获得的所有初始颈静脉球血氧饱和度测定数据进行了广泛分析。这些数据显示，57例患者（占研究人群的38%）的初始颈静脉球饱和度值异常，其中以颈静脉球血氧饱和度降低为主（45例患者出现）。这证实了早期报告，即脑损伤后的最初数小时内存在脑灌注紊乱和不足的高发生率。颈静脉球血氧饱和度降低尤其与全身因素有关（如29例患者出现脑灌注压降低，24例患者出现动脉血二氧化碳分压降低）。这些发现可能对重度颅脑损伤患者的急诊处理具有重要意义，因为更好地关注所有可能在创伤性损伤后早期降低脑灌注的全身因素，可能会改善患者的预后。
